Specific integrin [alpha] and {szligbeta} chain phosphorylations regulate LFA-1 activation through affinity-dependent and -independent mechanisms

Integrins are adhesion receptors that are crucial to the functions of multicellular organisms. Integrin-mediated adhesion is a complex process that involves both affinity regulation and cytoskeletal coupling, but the molecular mechanisms behind this process have remained incompletely understood. In...

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Veröffentlicht in:The Journal of cell biology 2005, Vol.171 (4), p.705-715
Hauptverfasser: Fagerholm, Susanna C, Hilden, Tiina J, Nurmi, Susanna M, Gahmberg, Carl G
Format: Artikel
Sprache:eng
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