DNA Immunization with Na⁺-K⁺ATPase (Sseat-6) Induces Protective Immunity to Larval Strongyloides stercoralis in Mice

Strongyloides stercoralis causes chronic asymptomatic infections which can be maintained in the human host for many decades. Identification and treatment of S. stercoralis-infected individuals is required because immunosuppression can lead to fatal hyperinfection. In this study, human immunoglobulin...

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Veröffentlicht in:	Infection and Immunity 2005-04, Vol.73 (4), p.2298-2305
Hauptverfasser:	Kerepesi, Laura A, Keiser, Paul B, Nolan, Thomas J, Schad, Gerhard A, Abraham, David, Nutman, Thomas B
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Helminth - immunology Female Fungal and Parasitic Infections Humans Immunization Immunoglobulin G - immunology Larva - immunology Mice Mice, Inbred BALB C Sodium-Potassium-Exchanging ATPase - genetics Sodium-Potassium-Exchanging ATPase - immunology Strongyloides stercoralis - immunology Strongyloidiasis - prevention & control Tropomyosin - genetics Tropomyosin - immunology Vaccines, DNA - immunology
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