Microencapsulation of Bacteriophage Felix O1 into Chitosan-Alginate Microspheres for Oral Delivery

This paper reports the development of microencapsulated bacteriophage Felix O1 for oral delivery using a chitosan-alginate-CaCl₂ system. In vitro studies were used to determine the effects of simulated gastric fluid (SGF) and bile salts on the viability of free and encapsulated phage. Free phage Fel...

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Veröffentlicht in:	Applied and Environmental Microbiology 2008-08, Vol.74 (15), p.4799-4805
Hauptverfasser:	Ma, Yongsheng, Pacan, Jennifer C, Wang, Qi, Xu, Yongping, Huang, Xiaoqing, Korenevsky, Anton, Sabour, Parviz M
Format:	Artikel
Sprache:	eng
Schlagworte:	Alginates Bacteria Bacteriophages - drug effects Bacteriophages - isolation & purification Bacteriophages - physiology Bacteriophages - ultrastructure Bile Biological and medical sciences Body fluids Chitosan Drug Compounding - methods Fundamental and applied biological sciences. Psychology Gastric Juice Gastrointestinal diseases Glucuronic Acid Hexuronic Acids Hydrogen-Ion Concentration Microbiology Pepsin A - pharmacology Public Health Microbiology Salmonella typhi - virology Simulation Studies
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