Early Impairment of Gut Function and Gut Flora Supporting a Role for Alteration of Gastrointestinal Mucosa in Human Immunodeficiency Virus Pathogenesis
Our results show that impairment of the gastrointestinal tracts in human immunodeficiency virus (HIV)-positive patients is present in the early phases of HIV disease. This impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters. These findings support the h...
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| Veröffentlicht in: | Journal of Clinical Microbiology 2008-02, Vol.46 (2), p.757-758 |
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| container_title | Journal of Clinical Microbiology |
| container_volume | 46 |
| creator | Gori, Andrea Tincati, Camilla Rizzardini, Giuliano Torti, Carlo Quirino, Tiziana Haarman, Monique Ben Amor, Kaouther van Schaik, Jacqueline Vriesema, Aldwin Knol, Jan Marchetti, Giulia Welling, Gjalt Clerici, Mario |
| description | Our results show that impairment of the gastrointestinal tracts in human immunodeficiency virus (HIV)-positive patients is present in the early phases of HIV disease. This impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters. These findings support the hypothesis that alterations at the gastrointestinal-tract level are a key factor in HIV pathogenesis. |
| doi_str_mv | 10.1128/JCM.01729-07 |
| format | Article |
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This impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters. These findings support the hypothesis that alterations at the gastrointestinal-tract level are a key factor in HIV pathogenesis.</description><identifier>ISSN: 0095-1137</identifier><identifier>EISSN: 1098-660X</identifier><identifier>EISSN: 1098-5530</identifier><identifier>DOI: 10.1128/JCM.01729-07</identifier><identifier>PMID: 18094140</identifier><identifier>CODEN: JCMIDW</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Biological and medical sciences ; Feces - chemistry ; Feces - microbiology ; Fundamental and applied biological sciences. 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This impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters. These findings support the hypothesis that alterations at the gastrointestinal-tract level are a key factor in HIV pathogenesis.</description><subject>Biological and medical sciences</subject><subject>Feces - chemistry</subject><subject>Feces - microbiology</subject><subject>Fundamental and applied biological sciences. 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Psychology</topic><topic>Gastrointestinal Tract - immunology</topic><topic>Gastrointestinal Tract - microbiology</topic><topic>Gastrointestinal Tract - pathology</topic><topic>HIV - physiology</topic><topic>HIV Infections - complications</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Inflammation - immunology</topic><topic>Inflammation - microbiology</topic><topic>Inflammation - pathology</topic><topic>Intestinal Mucosa - immunology</topic><topic>Intestinal Mucosa - pathology</topic><topic>Intestinal Mucosa - physiopathology</topic><topic>Leukocyte L1 Antigen Complex - analysis</topic><topic>Microbiology</topic><topic>Miscellaneous</topic><topic>Virology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gori, Andrea</creatorcontrib><creatorcontrib>Tincati, Camilla</creatorcontrib><creatorcontrib>Rizzardini, Giuliano</creatorcontrib><creatorcontrib>Torti, Carlo</creatorcontrib><creatorcontrib>Quirino, Tiziana</creatorcontrib><creatorcontrib>Haarman, Monique</creatorcontrib><creatorcontrib>Ben Amor, Kaouther</creatorcontrib><creatorcontrib>van Schaik, Jacqueline</creatorcontrib><creatorcontrib>Vriesema, Aldwin</creatorcontrib><creatorcontrib>Knol, Jan</creatorcontrib><creatorcontrib>Marchetti, Giulia</creatorcontrib><creatorcontrib>Welling, Gjalt</creatorcontrib><creatorcontrib>Clerici, Mario</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Journal of Clinical Microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gori, Andrea</au><au>Tincati, Camilla</au><au>Rizzardini, Giuliano</au><au>Torti, Carlo</au><au>Quirino, Tiziana</au><au>Haarman, Monique</au><au>Ben Amor, Kaouther</au><au>van Schaik, Jacqueline</au><au>Vriesema, Aldwin</au><au>Knol, Jan</au><au>Marchetti, Giulia</au><au>Welling, Gjalt</au><au>Clerici, Mario</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Early Impairment of Gut Function and Gut Flora Supporting a Role for Alteration of Gastrointestinal Mucosa in Human Immunodeficiency Virus Pathogenesis</atitle><jtitle>Journal of Clinical Microbiology</jtitle><addtitle>J Clin Microbiol</addtitle><date>2008-02-01</date><risdate>2008</risdate><volume>46</volume><issue>2</issue><spage>757</spage><epage>758</epage><pages>757-758</pages><issn>0095-1137</issn><eissn>1098-660X</eissn><eissn>1098-5530</eissn><coden>JCMIDW</coden><abstract>Our results show that impairment of the gastrointestinal tracts in human immunodeficiency virus (HIV)-positive patients is present in the early phases of HIV disease. This impairment is associated with alterations in gut microbiota and intestinal inflammatory parameters. These findings support the hypothesis that alterations at the gastrointestinal-tract level are a key factor in HIV pathogenesis.</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>18094140</pmid><doi>10.1128/JCM.01729-07</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | Journal of Clinical Microbiology, 2008-02, Vol.46 (2), p.757-758 |
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| source | American Society for Microbiology; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Biological and medical sciences Feces - chemistry Feces - microbiology Fundamental and applied biological sciences. Psychology Gastrointestinal Tract - immunology Gastrointestinal Tract - microbiology Gastrointestinal Tract - pathology HIV - physiology HIV Infections - complications Human immunodeficiency virus Humans Inflammation - immunology Inflammation - microbiology Inflammation - pathology Intestinal Mucosa - immunology Intestinal Mucosa - pathology Intestinal Mucosa - physiopathology Leukocyte L1 Antigen Complex - analysis Microbiology Miscellaneous Virology |
| title | Early Impairment of Gut Function and Gut Flora Supporting a Role for Alteration of Gastrointestinal Mucosa in Human Immunodeficiency Virus Pathogenesis |
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