Molecular cloning, in vitro expression and bioactivity of goose B-cell activating factor

B-cell activating factor (BAFF), belonging to the TNF family, is critical for B cell survival and maturation. cDNA of goose BAFF (gBAFF) was amplified from goose spleen by RT-PCR. The open reading frame (ORF) of gBAFF encodes a protein of 288-amino acid. The gBAFF shows 98, 92, 44 and 55% amino acid...

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Veröffentlicht in:	Veterinary immunology and immunopathology 2006, Vol.118, p.113-120
Hauptverfasser:	Dan, W.B, Guan, Z.B, Zhang, C, Li, B.C, Zhang, J, Zhang, S.Q
Format:	Artikel
Sprache:	eng
Schlagworte:	amino acid sequences B-cell activating factor B-lymphocytes bioactive properties bursa of Fabricius cell physiology complementary DNA cross reaction geese gene expression immune system lymphocyte proliferation messenger RNA molecular cloning molecular sequence data molecular weight nucleotide sequences phylogeny protein synthesis species differences spleen thymus gland transcription (genetics) tumor necrosis factors
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