Positive association between DNA strand breaks in peripheral blood mononuclear cells and polyunsaturated fatty acids in red blood cells from women

Lipid peroxidation of polyunsaturated fatty acids (PUFA) generates reactive products that may cause DNA damage. To examine the possible relationship between DNA damage in peripheral blood mononuclear cells (PBMC) and the concentration of PUFA in red blood cells (RBC), endogenous DNA strand breaks, f...

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Veröffentlicht in:	Nutrition and cancer 2007-01, Vol.59 (1), p.21-28
Hauptverfasser:	Thorlaksdottir, A.Y, Jonsson, J.J, Tryggvadottir, L, Skuladottir, G.V, Petursdottir, A.L, Ogmundsdottir, H.M, Eyfjord, J.E, Hardardottir, I
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Biological and medical sciences Chromatography, Gas - methods Comet Assay DNA Breaks DNA damage DNA Damage - drug effects DNA strand breaks docosahexaenoic acid Epidemiology erythrocytes Erythrocytes - chemistry fatty acid composition Fatty Acids, Unsaturated - analysis Fatty Acids, Unsaturated - pharmacology Female gas chromatography Humans hydrogen peroxide Leukocytes, Mononuclear - chemistry linoleic acid lipid content Lipid Peroxidation Medical sciences Middle Aged monocytes oleic acid omega-3 fatty acids Other treatments Oxidative Stress palmitic acid peroxides polyunsaturated fatty acids saturated fatty acids Smoking Treatment. General aspects Tumors women
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