Monomeric Expression of Bovine β₂-Integrin Subunits Reveals Their Role in Mannheimia haemolytica Leukotoxin-Induced Biological Effects

The ruminant-specific leukotoxin (Lkt) of Mannheimia haemolytica is the key virulence factor contributing to the pathogenesis of lung injury in bovine pneumonic pasteurellosis. Previous studies by us and others indicate that M. haemolytica Lkt binds to CD18, the β subunit of bovine β₂-integrins on l...

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Veröffentlicht in:	Infection and Immunity 2007-10, Vol.75 (10), p.5004-5010
Hauptverfasser:	Dassanayake, Rohana P, Maheswaran, Samuel K, Srikumaran, Subramaniam
Format:	Artikel
Sprache:	eng
Schlagworte:	Molecular Pathogenesis
Online-Zugang:	Volltext
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