Essential role for MFG-E8 as ligand for αvβ5 integrin in diurnal retinal phagocytosis

The integrin receptor αvβ5 controls two independent forms of interactions of the retinal pigment epithelium (RPE) with adjacent photoreceptor outer segments that are essential for vision. αvβ5 localizes specifically to apical microvilli of the RPE and contributes to retinal adhesion that maintains R...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2007-07, Vol.104 (29), p.12005-12010
Hauptverfasser:	Nandrot, Emeline F, Anand, Monika, Almeida, Dena, Atabai, Kamran, Sheppard, Dean, Finnemann, Silvia C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesion Biological Sciences Immunoblotting Integrins Ligands Phagocytosis Phagosomes Photoreceptors Receptors Retina Retinal pigments
Online-Zugang:	Volltext
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