Piezotolerant Small-Colony Variants with Increased Thermotolerance, Antibiotic Susceptibility, and Low Invasiveness in a Clonal Staphylococcus aureus Population

Following a pressure treatment of a clonal Staphylococcus aureus culture with 400 MPa for 30 min, piezotolerant variants were isolated. Among 21 randomly selected survivors, 9 were piezotolerant and all formed small colonies on several agar media. The majority of the isolates showed increased thermo...

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Veröffentlicht in:	Applied and Environmental Microbiology 2007-03, Vol.73 (6), p.1873-1881
Hauptverfasser:	Karatzas, Kimon A.G, Zervos, Angelos, Tassou, Chrysoula C, Mallidis, Costas G, Humphrey, Tom J
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - pharmacology Antibiotics Bacteria Bacterial Proteins - genetics Bacteriology Biological and medical sciences Caco-2 Cells DNA Fingerprinting DNA-Binding Proteins - genetics Drug resistance Fundamental and applied biological sciences. Psychology Genetics Genotype & phenotype Hot Temperature Humans Hydrostatic Pressure Listeria monocytogenes Microbial Sensitivity Tests Microbiology Mutation Physiology and Biotechnology Pigments, Biological - biosynthesis Proteins Repressor Proteins - genetics Sequence Analysis, DNA Staphylococcal Protein A - analysis Staphylococcus aureus Staphylococcus aureus - drug effects Staphylococcus aureus - genetics Staphylococcus aureus - pathogenicity Staphylococcus aureus - physiology Virulence - genetics
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