Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene

The Evi5 oncogene has recently been shown to regulate the stability and accumulation of critical G₁ cell cycle factors including Emi1, an inhibitor of the anaphase-promoting complex/cyclosome, and cyclin A. Sequence analysis of the amino terminus of Evi5 reveals a Tre-2, Bub2, Cdc16 domain, which ha...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2007-01, Vol.104 (4), p.1236-1241
Hauptverfasser:	Westlake, Christopher J, Junutula, Jagath R, Simon, Glenn C, Pilli, Manohar, Prekeris, Rytis, Scheller, Richard H, Jackson, Peter K, Eldridge, Adam G
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Biological Sciences Cell Cycle Cell Line Cellular biology Centrosomes Cytokines Cytokinesis Endosomes Epithelial cells Gene expression regulation GTP Phosphohydrolases - metabolism Humans I-kappa B Kinase - metabolism Interphase Nuclear Proteins - genetics Nuclear Proteins - metabolism Oncogenes Protein Binding Proteins rab GTP-Binding Proteins - metabolism Recycling Surface Plasmon Resonance
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