Pyrrolylbenzodiazepinones
The present invention relates to compounds of the formula wherein R is methyl, fluorine or bromine, and pharmaceutically acceptable salts thereof. Utilizable as therapeutically active agents especially for the treatment of retroviral infections, particularly HIV infections, they can be prepared in a...
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| creator | MINGU HSU |
| description | The present invention relates to compounds of the formula wherein R is methyl, fluorine or bromine, and pharmaceutically acceptable salts thereof. Utilizable as therapeutically active agents especially for the treatment of retroviral infections, particularly HIV infections, they can be prepared in a manner known per se by a process which comprises reacting 2-bromo-2'-(1H-pyrrol-2-yl-carbonyl)acetanilide, correspondingly substituted by R in the 4'-position, with ammonia and cyclizing the obtained 2-aminoacetanilide with pivalic acid. |
| format | Patent |
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Utilizable as therapeutically active agents especially for the treatment of retroviral infections, particularly HIV infections, they can be prepared in a manner known per se by a process which comprises reacting 2-bromo-2'-(1H-pyrrol-2-yl-carbonyl)acetanilide, correspondingly substituted by R in the 4'-position, with ammonia and cyclizing the obtained 2-aminoacetanilide with pivalic acid.</description><edition>5</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1993</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19930819&DB=EPODOC&CC=ZA&NR=93285B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19930819&DB=EPODOC&CC=ZA&NR=93285B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MINGU HSU</creatorcontrib><title>Pyrrolylbenzodiazepinones</title><description>The present invention relates to compounds of the formula wherein R is methyl, fluorine or bromine, and pharmaceutically acceptable salts thereof. Utilizable as therapeutically active agents especially for the treatment of retroviral infections, particularly HIV infections, they can be prepared in a manner known per se by a process which comprises reacting 2-bromo-2'-(1H-pyrrol-2-yl-carbonyl)acetanilide, correspondingly substituted by R in the 4'-position, with ammonia and cyclizing the obtained 2-aminoacetanilide with pivalic acid.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1993</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJAMqCwqys-pzElKzavKT8lMrEotyMzLz0st5mFgTUvMKU7lhdLcDLJuriHOHrqpBfnxqcUFicmpeakl8VGOlsZGFqZOxoTkAXcoIhg</recordid><startdate>19930819</startdate><enddate>19930819</enddate><creator>MINGU HSU</creator><scope>EVB</scope></search><sort><creationdate>19930819</creationdate><title>Pyrrolylbenzodiazepinones</title><author>MINGU HSU</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ZA93285B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1993</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>MINGU HSU</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MINGU HSU</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pyrrolylbenzodiazepinones</title><date>1993-08-19</date><risdate>1993</risdate><abstract>The present invention relates to compounds of the formula wherein R is methyl, fluorine or bromine, and pharmaceutically acceptable salts thereof. Utilizable as therapeutically active agents especially for the treatment of retroviral infections, particularly HIV infections, they can be prepared in a manner known per se by a process which comprises reacting 2-bromo-2'-(1H-pyrrol-2-yl-carbonyl)acetanilide, correspondingly substituted by R in the 4'-position, with ammonia and cyclizing the obtained 2-aminoacetanilide with pivalic acid.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Pyrrolylbenzodiazepinones |
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