PROCESS FOR THE PREPARATION OF A MACROLIDE COMPOUND

A process for preparing the compound of formula (I) which comprises treating the corresponding 23 alpha - compound sequentially with (i) oxalyl chloride and (ii) 2-mercaptopyridine-N-oxide, a catalytic amount of an organic base, and a thiol.

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Bibliographische Detailangaben
Hauptverfasser: SIMON C. DOLAN, MICHAEL V.J. RAMSAY
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A process for preparing the compound of formula (I) which comprises treating the corresponding 23 alpha - compound sequentially with (i) oxalyl chloride and (ii) 2-mercaptopyridine-N-oxide, a catalytic amount of an organic base, and a thiol.