ANTICOCCIDAL SUBSTANCE AND ITS PREPARATION

A newa antibacterial and coccidiostatic antibiotic (31,559 RP), and its metal salts and salts with nitrogen bases, are obtained by culturing and new strain Streptomyces hygroscopicus DS 24,367 (NRRL 5787) in a suitable medium under aerobic conditions and isolating the 31,559 RP, opt. in salts form....

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Hauptverfasser: FLORENT J, LUNEL J, MANCY D
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creator FLORENT J
LUNEL J
MANCY D
description A newa antibacterial and coccidiostatic antibiotic (31,559 RP), and its metal salts and salts with nitrogen bases, are obtained by culturing and new strain Streptomyces hygroscopicus DS 24,367 (NRRL 5787) in a suitable medium under aerobic conditions and isolating the 31,559 RP, opt. in salts form. 31,559 RP can be used (i) to treat bacterial infections, esp. due to Gram positive bacteria (e.g. MIC=0.2-2.5 mu g/ml against Staph. aureus, Sarcina lutea, Strept. faecalis, Strept. pyogenes, Dipl. pneumoniae, B. subtilis and B. cereus); (ii) to treat coccidiosis in poultry due to Eimeria. tenella and E. acervulina, (iii) as a feed additive to promote the growth of ruminants and control swine dysentery, and (iv) to treat malaria (active against exptl. Plasmodium infections in chickens and mice). The LD50 of the Na salt is 150 mg/kg (p.o., chicken).
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
FODDER
FOODS OR FOODSTUFFS
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROCESSES USING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
VINEGAR
WINE
title ANTICOCCIDAL SUBSTANCE AND ITS PREPARATION
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