SOLID FORMS OF 2-[(4-{6-[(4-CYANO-2-FLUOROBENZYL)OXY]PYRIDIN-2-YL}PIPERIDIN-1-YL)METHYL]-1-[(2S)-OXETAN-2-YLMETHYL]-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

SOLID FORMS OF 2-[(4-{6-[(4-CYANO-2-FLUOROBENZYL)OXY]PYRIDIN-2-YL}PIPERIDIN-1-YL)METHYL]-1-[(2S)-OXETAN-2-YLMETHYL]-1H-BENZIMIDAZOLE-6-CARBOXYLIC ACID, 1,3-DIHYDROXY-2-(HYDROXYMETHYL)PROPAN-2-AMINE SALT

The invention provides solid forms of 2-[(4-{6-[(4-Cyano-2- fluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(2S) -oxetan-2-ylmethyl]-1lH-benzimidazole-6-carboxylic acid, 1,3- dihydroxy-2-(hydroxymethyl)propan-2-amine salt for example, Form 1 or Form 2; as well as pharmaceutical compositions,...

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Bibliographische Detailangaben
Hauptverfasser: TAYLOR, Lisa Jane, GRIFFITH, David Andrew, CLARK, Wesley Dewitt, JIAO, Wenhua, SAMAS, Brian Matthew, BAGLEY, Scott W
Format: Patent
Sprache:eng
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Zusammenfassung:The invention provides solid forms of 2-[(4-{6-[(4-Cyano-2- fluorobenzyl)oxy]pyridin-2-yl}piperidin-1-yl)methyl]-1-[(2S) -oxetan-2-ylmethyl]-1lH-benzimidazole-6-carboxylic acid, 1,3- dihydroxy-2-(hydroxymethyl)propan-2-amine salt for example, Form 1 or Form 2; as well as pharmaceutical compositions, and the uses thereof in treating diseases, conditions or disorders modulated by GLP-1 R in a mammal, such as a human. Formula (I)