MONO- OR DI-SUBSTITUTED INDOLE DERIVATIVES AS DENGUE VIRAL REPLICATION INHIBITORS

The present invention relates to mono- or di-substituted indole compounds, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The pres...

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Bibliographische Detailangaben
Hauptverfasser: MARCHAND, Arnaud Didier M, JONCKERS, Tim Hugo Maria, BARDIOT, Dorothée Alice Marie-Eve, RABOISSON, Pierre Jean-Marie Bernard, BONFANTI, Jean-François, KESTELEYN, Bart Rudolf Romanie
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to mono- or di-substituted indole compounds, methods to prevent or treat dengue viral infections by using said compounds and also relates to said compounds for use as a medicine, more preferably for use as a medicine to treat or prevent dengue viral infections. The present invention furthermore relates to pharmaceutical compositions or combination preparations of the compounds, to the compositions or preparations for use as a medicine, more preferably for the prevention or treatment of dengue viral infections. The invention also relates to processes for preparation of the compounds.