CD47 ANTIBODIES, METHODS, AND USES

CD47 ANTIBODIES, METHODS, AND USES

The present disclosure relates generally to monoclonal antibodies that specifically bind to CD47, more specifically to CD47 antibodies that do not have significant platelet aggregation activity and do not have significant hemagglutination activity. Methods of generating these antibodies and methods...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CARDOSO, Rosa, PIETSCH, Christine, DONG, Jianying, ZHOU, Hong Mimi
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure relates generally to monoclonal antibodies that specifically bind to CD47, more specifically to CD47 antibodies that do not have significant platelet aggregation activity and do not have significant hemagglutination activity. Methods of generating these antibodies and methods of using these monoclonal antibodies as therapeutics are also provided.