METHOD FOR PURIFYING CYS-LINKED ANTIBODY-DRUG CONJUGATES

The present invention relates to a method for purifying a mixture of cysteine-linked antibody-drug conjugates, wherein the amount of non-conjugated antibody is in the range of 0-40% by weight, using hydrophobic interaction chromatography (HIC). The mixture is loaded onto a preparative HIC column usi...

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Hauptverfasser:	RUUD MARTIN VERSTEGEN, RUDY GERARDUS ELISABETH COUMANS, GUY ROO DE
Format:	Patent
Sprache:	eng
Online-Zugang:	Volltext bestellen
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