KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE

KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE

Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also...

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Hauptverfasser: CLARE, Michael, RIENHOFF, Jr. Hugh Young, MCCALL, John M
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Sprache:eng
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creator CLARE, Michael
RIENHOFF, Jr. Hugh Young
MCCALL, John M
description Disclosed herein are new compounds and compositions and their application as pharmaceuticals for the treatment of diseases. Methods of inhibition of KDM1A, methods of increasing gamma globin gene expression, and methods to induce differentiation of cancer cells in a human or animal subject are also provided for the treatment of diseases such as acute myelogenous leukemia.
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title KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE
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