PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS
The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | GRILLOT ANNE-LAURE BENNANI YOUSSEF LAAFIRET PEROLA EMANUELE LE TIRAN ARNAUD CHARIFSON PAUL S O'DOWD HARDWIN |
| description | The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_ZA201305233B</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ZA201305233B</sourcerecordid><originalsourceid>FETCH-epo_espacenet_ZA201305233B3</originalsourceid><addsrcrecordid>eNrjZDAMiAzy9PV08fRzVXCPDHIMdlVw9HNRCPEP8PcM9vd1BYt4hil4-nl4OnmG-AcF8zCwpiXmFKfyQmluBkU31xBnD93Ugvz41OKCxOTUvNSS-ChHIwNDYwNTI2NjJ2Ni1AAAc2sm0A</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS</title><source>esp@cenet</source><creator>GRILLOT ANNE-LAURE ; BENNANI YOUSSEF LAAFIRET ; PEROLA EMANUELE ; LE TIRAN ARNAUD ; CHARIFSON PAUL S ; O'DOWD HARDWIN</creator><creatorcontrib>GRILLOT ANNE-LAURE ; BENNANI YOUSSEF LAAFIRET ; PEROLA EMANUELE ; LE TIRAN ARNAUD ; CHARIFSON PAUL S ; O'DOWD HARDWIN</creatorcontrib><description>The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.</description><language>eng</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2014</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141126&DB=EPODOC&CC=ZA&NR=201305233B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20141126&DB=EPODOC&CC=ZA&NR=201305233B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GRILLOT ANNE-LAURE</creatorcontrib><creatorcontrib>BENNANI YOUSSEF LAAFIRET</creatorcontrib><creatorcontrib>PEROLA EMANUELE</creatorcontrib><creatorcontrib>LE TIRAN ARNAUD</creatorcontrib><creatorcontrib>CHARIFSON PAUL S</creatorcontrib><creatorcontrib>O'DOWD HARDWIN</creatorcontrib><title>PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS</title><description>The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2014</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAMiAzy9PV08fRzVXCPDHIMdlVw9HNRCPEP8PcM9vd1BYt4hil4-nl4OnmG-AcF8zCwpiXmFKfyQmluBkU31xBnD93Ugvz41OKCxOTUvNSS-ChHIwNDYwNTI2NjJ2Ni1AAAc2sm0A</recordid><startdate>20141126</startdate><enddate>20141126</enddate><creator>GRILLOT ANNE-LAURE</creator><creator>BENNANI YOUSSEF LAAFIRET</creator><creator>PEROLA EMANUELE</creator><creator>LE TIRAN ARNAUD</creator><creator>CHARIFSON PAUL S</creator><creator>O'DOWD HARDWIN</creator><scope>EVB</scope></search><sort><creationdate>20141126</creationdate><title>PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS</title><author>GRILLOT ANNE-LAURE ; BENNANI YOUSSEF LAAFIRET ; PEROLA EMANUELE ; LE TIRAN ARNAUD ; CHARIFSON PAUL S ; O'DOWD HARDWIN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ZA201305233B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2014</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GRILLOT ANNE-LAURE</creatorcontrib><creatorcontrib>BENNANI YOUSSEF LAAFIRET</creatorcontrib><creatorcontrib>PEROLA EMANUELE</creatorcontrib><creatorcontrib>LE TIRAN ARNAUD</creatorcontrib><creatorcontrib>CHARIFSON PAUL S</creatorcontrib><creatorcontrib>O'DOWD HARDWIN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GRILLOT ANNE-LAURE</au><au>BENNANI YOUSSEF LAAFIRET</au><au>PEROLA EMANUELE</au><au>LE TIRAN ARNAUD</au><au>CHARIFSON PAUL S</au><au>O'DOWD HARDWIN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS</title><date>2014-11-26</date><risdate>2014</risdate><abstract>The present invention relates to a compound of formula (I) or a pharmaceutically acceptable salt thereof wherein X and R are as defined herein. The compounds of formula (I) are useful as gyrase and/or topoisomerase IV inhibitors for treating bacterial infections. The compounds of formula (I) either possess a broad range of anti-bacterial activity and advantageous toxicological properties or are prodrugs of compounds having said activity.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_ZA201305233B |
| source | esp@cenet |
| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PYRIMIDINE GYRASE AND TOPOISOMERASE IV INHIBITORS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-09T17%3A46%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=GRILLOT%20ANNE-LAURE&rft.date=2014-11-26&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EZA201305233B%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |