TRISUBSTITUTED 1,2,4-TRIAZOLES

The present invention relates to 3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to posit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	VAN ROOSBROECK YVES EMIEL MARIA, LESAGE ANNE SIMONE JOSEPHINE, VAN DEN KEYBUS FRANS ALFONS MARIA, DE BRUYN MARCEL FRANS LEOPOLD, DINKLO THEODORUS, ZHUANG WEI, MACDONALD GREGOR JAMES, THURING JOHANNES WILHELMUS JOHN F, DUFFY JAMES EDWARD STEWART
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to 3-aniline-5-aryl triazole derivatives and analogues or pharmaceutically acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy, according to Formula (I). The invention particularly relates to positive allosteric modulators of nicotinic acetylcholine receptors, such positive allosteric modulator having the capability to increase the efficacy of nicotinic receptor agonists.