Sphingosine Kinase Inhibitors

The invention relates to substituted adamantane compounds, pharmaceutical compositions thereof, processes for their preparation, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angiogenic disease.

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Hauptverfasser: FRENCH, KEVIN, J, ZHUANG, YAN, SMITH, CHARLES D
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Sprache:eng
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creator FRENCH, KEVIN, J
ZHUANG, YAN
SMITH, CHARLES D
description The invention relates to substituted adamantane compounds, pharmaceutical compositions thereof, processes for their preparation, and methods for inhibiting sphingosine kinase and for treating or preventing hyperproliferative disease, inflammatory disease, or angiogenic disease.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title Sphingosine Kinase Inhibitors
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