Improved crystalline form of the compound A-348441
There is provided a hemihydrate of (3 ,5 ,7α,12α)-7,12-dihydroxy-3-{2-[{4-[17 -hydroxy-3-oxo-17α-prop-1-ynylestra-4,9-dien-11 -yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern having major peaks at 2 =6.58±0.2, 8.54+0.2, 1...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | LEANNA, MARVIN ROBERT CINK, RUSSELL DREW TOMA, PASCAL H LONG, MICHELLE ANDREE ZOU, DAOZHONG |
| description | There is provided a hemihydrate of (3 ,5 ,7α,12α)-7,12-dihydroxy-3-{2-[{4-[17 -hydroxy-3-oxo-17α-prop-1-ynylestra-4,9-dien-11 -yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern having major peaks at 2 =6.58±0.2, 8.54+0.2, 12.28±0.2, and 19.68±0.2. This crystalline material is useful in the treatment of conditions associated with an excess of hepatic glucocorticoid response. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_ZA200800278B</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>ZA200800278B</sourcerecordid><originalsourceid>FETCH-epo_espacenet_ZA200800278B3</originalsourceid><addsrcrecordid>eNrjZDDyzC0oyi9LTVFILqosLknMycnMS1VIyy_KVchPUyjJSFVIzs8tyC_NS1Fw1DU2sTAxMeRhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfFRjkYGBhYGBkbmFk7GxKgBAE6ZKqo</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Improved crystalline form of the compound A-348441</title><source>esp@cenet</source><creator>LEANNA, MARVIN ROBERT ; CINK, RUSSELL DREW ; TOMA, PASCAL H ; LONG, MICHELLE ANDREE ; ZOU, DAOZHONG</creator><creatorcontrib>LEANNA, MARVIN ROBERT ; CINK, RUSSELL DREW ; TOMA, PASCAL H ; LONG, MICHELLE ANDREE ; ZOU, DAOZHONG</creatorcontrib><description>There is provided a hemihydrate of (3 ,5 ,7α,12α)-7,12-dihydroxy-3-{2-[{4-[17 -hydroxy-3-oxo-17α-prop-1-ynylestra-4,9-dien-11 -yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern having major peaks at 2 =6.58±0.2, 8.54+0.2, 12.28±0.2, and 19.68±0.2. This crystalline material is useful in the treatment of conditions associated with an excess of hepatic glucocorticoid response.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; STEROIDS</subject><creationdate>2009</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090325&DB=EPODOC&CC=ZA&NR=200800278B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25544,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20090325&DB=EPODOC&CC=ZA&NR=200800278B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LEANNA, MARVIN ROBERT</creatorcontrib><creatorcontrib>CINK, RUSSELL DREW</creatorcontrib><creatorcontrib>TOMA, PASCAL H</creatorcontrib><creatorcontrib>LONG, MICHELLE ANDREE</creatorcontrib><creatorcontrib>ZOU, DAOZHONG</creatorcontrib><title>Improved crystalline form of the compound A-348441</title><description>There is provided a hemihydrate of (3 ,5 ,7α,12α)-7,12-dihydroxy-3-{2-[{4-[17 -hydroxy-3-oxo-17α-prop-1-ynylestra-4,9-dien-11 -yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern having major peaks at 2 =6.58±0.2, 8.54+0.2, 12.28±0.2, and 19.68±0.2. This crystalline material is useful in the treatment of conditions associated with an excess of hepatic glucocorticoid response.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>STEROIDS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2009</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDDyzC0oyi9LTVFILqosLknMycnMS1VIyy_KVchPUyjJSFVIzs8tyC_NS1Fw1DU2sTAxMeRhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfFRjkYGBhYGBkbmFk7GxKgBAE6ZKqo</recordid><startdate>20090325</startdate><enddate>20090325</enddate><creator>LEANNA, MARVIN ROBERT</creator><creator>CINK, RUSSELL DREW</creator><creator>TOMA, PASCAL H</creator><creator>LONG, MICHELLE ANDREE</creator><creator>ZOU, DAOZHONG</creator><scope>EVB</scope></search><sort><creationdate>20090325</creationdate><title>Improved crystalline form of the compound A-348441</title><author>LEANNA, MARVIN ROBERT ; CINK, RUSSELL DREW ; TOMA, PASCAL H ; LONG, MICHELLE ANDREE ; ZOU, DAOZHONG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ZA200800278B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2009</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>STEROIDS</topic><toplevel>online_resources</toplevel><creatorcontrib>LEANNA, MARVIN ROBERT</creatorcontrib><creatorcontrib>CINK, RUSSELL DREW</creatorcontrib><creatorcontrib>TOMA, PASCAL H</creatorcontrib><creatorcontrib>LONG, MICHELLE ANDREE</creatorcontrib><creatorcontrib>ZOU, DAOZHONG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LEANNA, MARVIN ROBERT</au><au>CINK, RUSSELL DREW</au><au>TOMA, PASCAL H</au><au>LONG, MICHELLE ANDREE</au><au>ZOU, DAOZHONG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Improved crystalline form of the compound A-348441</title><date>2009-03-25</date><risdate>2009</risdate><abstract>There is provided a hemihydrate of (3 ,5 ,7α,12α)-7,12-dihydroxy-3-{2-[{4-[17 -hydroxy-3-oxo-17α-prop-1-ynylestra-4,9-dien-11 -yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern having major peaks at 2 =6.58±0.2, 8.54+0.2, 12.28±0.2, and 19.68±0.2. This crystalline material is useful in the treatment of conditions associated with an excess of hepatic glucocorticoid response.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_ZA200800278B |
| source | esp@cenet |
| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STEROIDS |
| title | Improved crystalline form of the compound A-348441 |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T06%3A10%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=LEANNA,%20MARVIN%20ROBERT&rft.date=2009-03-25&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EZA200800278B%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |