Pyrido(3,2D)pyrimidines and pharmaceutical compositions useful for medical treatment
This invention relates to substituted pyrido(3,2-d)pyrimidine derivatives, their pharmaceutically acceptable salts, N-oxides, solvates, pro-drugs and enantiomers, possessing unexpectedly desirable pharmaceutical properties, in particular which are highly active immunosuppressive agents, and as such...
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| creator | DE JONGHE, STEVEN CESAR ALFONS GAO, LING-JIE PFLEIDERER, WOLFGANG EUGEN DOLUSIC, EDUARD HERDEWIJN, PIET ANDRE MAURITS MARIA |
| description | This invention relates to substituted pyrido(3,2-d)pyrimidine derivatives, their pharmaceutically acceptable salts, N-oxides, solvates, pro-drugs and enantiomers, possessing unexpectedly desirable pharmaceutical properties, in particular which are highly active immunosuppressive agents, and as such are useful in the treatment in transplant rejection and/or in the treatment of certain inflammatory diseases. These derivatives are also useful in preventing or treating cardiovascular disorders, disorders of the central nervous system, TNF-alpha related disorders, viral diseases (including hepatitis C), erectile dysfunction and cell proliferative disorders. |
| format | Patent |
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These derivatives are also useful in preventing or treating cardiovascular disorders, disorders of the central nervous system, TNF-alpha related disorders, viral diseases (including hepatitis C), erectile dysfunction and cell proliferative disorders.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Pyrido(3,2D)pyrimidines and pharmaceutical compositions useful for medical treatment |
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