Pyrimidine compounds
A pyrimidine derivative of formula (I) or (I'): wherein: R is a substituent as defined within; Q1 is optionally substituted phenyl, and Q1 bears a substituent of formula (Ia) wherein: X, Y , Y , Z, n, and m are as defined within; -NQ2 is an optionally substituted heterocyclic moiety containing...
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| creator | GLORIA ANNE BREAULT STEWART RUSSELL JAMES JANE ELIZABETH PEASE |
| description | A pyrimidine derivative of formula (I) or (I'): wherein: R is a substituent as defined within; Q1 is optionally substituted phenyl, and Q1 bears a substituent of formula (Ia) wherein: X, Y , Y , Z, n, and m are as defined within; -NQ2 is an optionally substituted heterocyclic moiety containing one hydrogen heteroatom and optionally containing a further heteroatom; or a pharmaceutically acceptable salt in vivo hydrolysable ester thereof; are useful as anti-cancer agents. Processes for their manufacture and pharmaceutical compositions containing them are described. |
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Processes for their manufacture and pharmaceutical compositions containing them are described.</description><edition>7</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2002</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20021202&DB=EPODOC&CC=ZA&NR=200107252B$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76294</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20021202&DB=EPODOC&CC=ZA&NR=200107252B$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>GLORIA ANNE BREAULT</creatorcontrib><creatorcontrib>STEWART RUSSELL JAMES</creatorcontrib><creatorcontrib>JANE ELIZABETH PEASE</creatorcontrib><title>Pyrimidine compounds</title><description>A pyrimidine derivative of formula (I) or (I'): wherein: R is a substituent as defined within; Q1 is optionally substituted phenyl, and Q1 bears a substituent of formula (Ia) wherein: X, Y , Y , Z, n, and m are as defined within; -NQ2 is an optionally substituted heterocyclic moiety containing one hydrogen heteroatom and optionally containing a further heteroatom; or a pharmaceutically acceptable salt in vivo hydrolysable ester thereof; are useful as anti-cancer agents. Processes for their manufacture and pharmaceutical compositions containing them are described.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2002</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZBAJqCzKzM1MycxLVUjOzy3IL81LKeZhYE1LzClO5YXS3AyKbq4hzh66qQX58anFBYnJqXmpJfFRjkYGBoYG5kamRk7GxKgBAGooIQk</recordid><startdate>20021202</startdate><enddate>20021202</enddate><creator>GLORIA ANNE BREAULT</creator><creator>STEWART RUSSELL JAMES</creator><creator>JANE ELIZABETH PEASE</creator><scope>EVB</scope></search><sort><creationdate>20021202</creationdate><title>Pyrimidine compounds</title><author>GLORIA ANNE BREAULT ; STEWART RUSSELL JAMES ; JANE ELIZABETH PEASE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_ZA200107252B3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2002</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>GLORIA ANNE BREAULT</creatorcontrib><creatorcontrib>STEWART RUSSELL JAMES</creatorcontrib><creatorcontrib>JANE ELIZABETH PEASE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>GLORIA ANNE BREAULT</au><au>STEWART RUSSELL JAMES</au><au>JANE ELIZABETH PEASE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Pyrimidine compounds</title><date>2002-12-02</date><risdate>2002</risdate><abstract>A pyrimidine derivative of formula (I) or (I'): wherein: R is a substituent as defined within; Q1 is optionally substituted phenyl, and Q1 bears a substituent of formula (Ia) wherein: X, Y , Y , Z, n, and m are as defined within; -NQ2 is an optionally substituted heterocyclic moiety containing one hydrogen heteroatom and optionally containing a further heteroatom; or a pharmaceutically acceptable salt in vivo hydrolysable ester thereof; are useful as anti-cancer agents. Processes for their manufacture and pharmaceutical compositions containing them are described.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Pyrimidine compounds |
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