PROCESS FOR MAKING PHARMACEUTICALLY ACTIVE DERIVATIVES OF PYRIDAZONE

PROCESS FOR MAKING PHARMACEUTICALLY ACTIVE DERIVATIVES OF PYRIDAZONE

A novel method of preparing ethyl{6-[ethyl-(2-hydroxypropyl)amino]-3-pyridazinyl}hydrazinecarboxylate is disclosed, wherein 7-chloro-3-methyl-4-oxo-4H-pyridazino[6,1-c][1,2,4]triazine is treated with ethyl-(2-hydroxypropyl)amine. The corresponding amino derivative is hydrolized in mild conditions an...

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Hauptverfasser: PARRAVICINI F, PINZA M
Format: Patent
Sprache:eng
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CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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creator PARRAVICINI F
PINZA M
description A novel method of preparing ethyl{6-[ethyl-(2-hydroxypropyl)amino]-3-pyridazinyl}hydrazinecarboxylate is disclosed, wherein 7-chloro-3-methyl-4-oxo-4H-pyridazino[6,1-c][1,2,4]triazine is treated with ethyl-(2-hydroxypropyl)amine. The corresponding amino derivative is hydrolized in mild conditions and the hydrazino compound thus obtained is suitably acylated.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
title PROCESS FOR MAKING PHARMACEUTICALLY ACTIVE DERIVATIVES OF PYRIDAZONE
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