PROCESS FOR OBTAINING DIHYDROPYRIDINE DERIVATIVES

Dihydropyridine anti-ischaemic and antihypertensive agents of the formula: (I) where Y is -(CH2)2- or -(CH2)3-; R is aryl or heteroaryl; R1 and R2 are each independently C1-C4 alkyl or 2-methoxyethyl; and R3 and R4 are each independently C1-C4 alkyl or aryl-(C1-C4 alkyl); or R3 and R4 taken together...

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Hauptverfasser:	CAMPBELL S.F, STUBBS J.K, CROSS P.E
Format:	Patent
Sprache:	eng
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator	CAMPBELL S.F STUBBS J.K CROSS P.E
description	Dihydropyridine anti-ischaemic and antihypertensive agents of the formula: (I) where Y is -(CH2)2- or -(CH2)3-; R is aryl or heteroaryl; R1 and R2 are each independently C1-C4 alkyl or 2-methoxyethyl; and R3 and R4 are each independently C1-C4 alkyl or aryl-(C1-C4 alkyl); or R3 and R4 taken together with the nitrogen atom to which they are attached represent a group of the formula: where R5 is C1-C4 alkyl, aryl, aryl-(C1-C4 alkyl), benzhydryl; 2-methoxyethyl, 2-(N,N-di[C1-C4 alkyl]amino) ethyl, or cyclopropylmethyl; their pharmaceutically acceptable acid addition salts, processes for the preparation of the compounds, and pharmaceutical compositions containing them.
format	Patent
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and R3 and R4 are each independently C1-C4 alkyl or aryl-(C1-C4 alkyl); or R3 and R4 taken together with the nitrogen atom to which they are attached represent a group of the formula: where R5 is C1-C4 alkyl, aryl, aryl-(C1-C4 alkyl), benzhydryl; 2-methoxyethyl, 2-(N,N-di[C1-C4 alkyl]amino) ethyl, or cyclopropylmethyl; their pharmaceutically acceptable acid addition salts, processes for the preparation of the compounds, and pharmaceutical compositions containing them.</description><edition>3</edition><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1984</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19841231&DB=EPODOC&CC=YU&NR=55082A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19841231&DB=EPODOC&CC=YU&NR=55082A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CAMPBELL S.F</creatorcontrib><creatorcontrib>STUBBS J.K</creatorcontrib><creatorcontrib>CROSS P.E</creatorcontrib><title>PROCESS FOR OBTAINING DIHYDROPYRIDINE DERIVATIVES</title><description>Dihydropyridine anti-ischaemic and antihypertensive agents of the formula: (I) where Y is -(CH2)2- or -(CH2)3-; 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STUBBS J.K ; CROSS P.E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_YU55082A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1984</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CAMPBELL S.F</creatorcontrib><creatorcontrib>STUBBS J.K</creatorcontrib><creatorcontrib>CROSS P.E</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CAMPBELL S.F</au><au>STUBBS J.K</au><au>CROSS P.E</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR OBTAINING DIHYDROPYRIDINE DERIVATIVES</title><date>1984-12-31</date><risdate>1984</risdate><abstract>Dihydropyridine anti-ischaemic and antihypertensive agents of the formula: (I) where Y is -(CH2)2- or -(CH2)3-; 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subjects	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title	PROCESS FOR OBTAINING DIHYDROPYRIDINE DERIVATIVES
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