PROCESS FOR OBTAINING SOLID PHARMACEUTICAL COMPOUNDS
The present invention relates to a process for the preparation of regulated release solid pharmaceutical compositions comprising 4-(2'-nitro-phenyl)-2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydro-pyr idine (referred to further on as "nifedipine") as active ingredient which comprises a...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | KRISZTIAN M FEKETE M ERDOS S HEGEDUS A GORGENYI F BARCZAY E MANDI A CSORGO M TOMPE P TAJTHY E KENDERFI J |
| description | The present invention relates to a process for the preparation of regulated release solid pharmaceutical compositions comprising 4-(2'-nitro-phenyl)-2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydro-pyr idine (referred to further on as "nifedipine") as active ingredient which comprises admixing a solution or solutions of 1 part by weight of nifedipine, 0.1-1.5 parts by weight of one or more hydrophilizing agent(s) and 0.05-1.5 parts by weight of one or more retarding agent(s) formed with one or more identical or different solvent(s) completely or partly and applying the solution(s) thus obtained simultaneously or in succession onto an inert carrier, drying and sieving the product thus obtained and subsequently admixing the same with suitable conventional auxiliary agents and compressing the mixture thus obtained to tablets in a known manner and coating the tablets or filling the mixture into capsules. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_YU45890A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>YU45890A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_YU45890A3</originalsourceid><addsrcrecordid>eNrjZDAJCPJ3dg0OVnDzD1Lwdwpx9PTz9HNXCPb38XRRCPBwDPJ1dHYNDfF0dvRRcPb3DfAP9XMJ5mFgTUvMKU7lhdLcDLJuriHOHrqpBfnxqcUFicmpeakl8ZGhJqYWlgaOxoTkAbbUJjg</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>PROCESS FOR OBTAINING SOLID PHARMACEUTICAL COMPOUNDS</title><source>esp@cenet</source><creator>KRISZTIAN M ; FEKETE M ; ERDOS S ; HEGEDUS A ; GORGENYI F ; BARCZAY E ; MANDI A ; CSORGO M ; TOMPE P ; TAJTHY E ; KENDERFI J</creator><creatorcontrib>KRISZTIAN M ; FEKETE M ; ERDOS S ; HEGEDUS A ; GORGENYI F ; BARCZAY E ; MANDI A ; CSORGO M ; TOMPE P ; TAJTHY E ; KENDERFI J</creatorcontrib><description>The present invention relates to a process for the preparation of regulated release solid pharmaceutical compositions comprising 4-(2'-nitro-phenyl)-2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydro-pyr idine (referred to further on as "nifedipine") as active ingredient which comprises admixing a solution or solutions of 1 part by weight of nifedipine, 0.1-1.5 parts by weight of one or more hydrophilizing agent(s) and 0.05-1.5 parts by weight of one or more retarding agent(s) formed with one or more identical or different solvent(s) completely or partly and applying the solution(s) thus obtained simultaneously or in succession onto an inert carrier, drying and sieving the product thus obtained and subsequently admixing the same with suitable conventional auxiliary agents and compressing the mixture thus obtained to tablets in a known manner and coating the tablets or filling the mixture into capsules.</description><edition>5</edition><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1992</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19920528&DB=EPODOC&CC=YU&NR=45890A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19920528&DB=EPODOC&CC=YU&NR=45890A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KRISZTIAN M</creatorcontrib><creatorcontrib>FEKETE M</creatorcontrib><creatorcontrib>ERDOS S</creatorcontrib><creatorcontrib>HEGEDUS A</creatorcontrib><creatorcontrib>GORGENYI F</creatorcontrib><creatorcontrib>BARCZAY E</creatorcontrib><creatorcontrib>MANDI A</creatorcontrib><creatorcontrib>CSORGO M</creatorcontrib><creatorcontrib>TOMPE P</creatorcontrib><creatorcontrib>TAJTHY E</creatorcontrib><creatorcontrib>KENDERFI J</creatorcontrib><title>PROCESS FOR OBTAINING SOLID PHARMACEUTICAL COMPOUNDS</title><description>The present invention relates to a process for the preparation of regulated release solid pharmaceutical compositions comprising 4-(2'-nitro-phenyl)-2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydro-pyr idine (referred to further on as "nifedipine") as active ingredient which comprises admixing a solution or solutions of 1 part by weight of nifedipine, 0.1-1.5 parts by weight of one or more hydrophilizing agent(s) and 0.05-1.5 parts by weight of one or more retarding agent(s) formed with one or more identical or different solvent(s) completely or partly and applying the solution(s) thus obtained simultaneously or in succession onto an inert carrier, drying and sieving the product thus obtained and subsequently admixing the same with suitable conventional auxiliary agents and compressing the mixture thus obtained to tablets in a known manner and coating the tablets or filling the mixture into capsules.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1992</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDAJCPJ3dg0OVnDzD1Lwdwpx9PTz9HNXCPb38XRRCPBwDPJ1dHYNDfF0dvRRcPb3DfAP9XMJ5mFgTUvMKU7lhdLcDLJuriHOHrqpBfnxqcUFicmpeakl8ZGhJqYWlgaOxoTkAbbUJjg</recordid><startdate>19920528</startdate><enddate>19920528</enddate><creator>KRISZTIAN M</creator><creator>FEKETE M</creator><creator>ERDOS S</creator><creator>HEGEDUS A</creator><creator>GORGENYI F</creator><creator>BARCZAY E</creator><creator>MANDI A</creator><creator>CSORGO M</creator><creator>TOMPE P</creator><creator>TAJTHY E</creator><creator>KENDERFI J</creator><scope>EVB</scope></search><sort><creationdate>19920528</creationdate><title>PROCESS FOR OBTAINING SOLID PHARMACEUTICAL COMPOUNDS</title><author>KRISZTIAN M ; FEKETE M ; ERDOS S ; HEGEDUS A ; GORGENYI F ; BARCZAY E ; MANDI A ; CSORGO M ; TOMPE P ; TAJTHY E ; KENDERFI J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_YU45890A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1992</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>KRISZTIAN M</creatorcontrib><creatorcontrib>FEKETE M</creatorcontrib><creatorcontrib>ERDOS S</creatorcontrib><creatorcontrib>HEGEDUS A</creatorcontrib><creatorcontrib>GORGENYI F</creatorcontrib><creatorcontrib>BARCZAY E</creatorcontrib><creatorcontrib>MANDI A</creatorcontrib><creatorcontrib>CSORGO M</creatorcontrib><creatorcontrib>TOMPE P</creatorcontrib><creatorcontrib>TAJTHY E</creatorcontrib><creatorcontrib>KENDERFI J</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KRISZTIAN M</au><au>FEKETE M</au><au>ERDOS S</au><au>HEGEDUS A</au><au>GORGENYI F</au><au>BARCZAY E</au><au>MANDI A</au><au>CSORGO M</au><au>TOMPE P</au><au>TAJTHY E</au><au>KENDERFI J</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR OBTAINING SOLID PHARMACEUTICAL COMPOUNDS</title><date>1992-05-28</date><risdate>1992</risdate><abstract>The present invention relates to a process for the preparation of regulated release solid pharmaceutical compositions comprising 4-(2'-nitro-phenyl)-2,6-dimethyl-3,5-dimethoxycarbonyl-1,4-dihydro-pyr idine (referred to further on as "nifedipine") as active ingredient which comprises admixing a solution or solutions of 1 part by weight of nifedipine, 0.1-1.5 parts by weight of one or more hydrophilizing agent(s) and 0.05-1.5 parts by weight of one or more retarding agent(s) formed with one or more identical or different solvent(s) completely or partly and applying the solution(s) thus obtained simultaneously or in succession onto an inert carrier, drying and sieving the product thus obtained and subsequently admixing the same with suitable conventional auxiliary agents and compressing the mixture thus obtained to tablets in a known manner and coating the tablets or filling the mixture into capsules.</abstract><edition>5</edition><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_YU45890A |
| source | esp@cenet |
| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | PROCESS FOR OBTAINING SOLID PHARMACEUTICAL COMPOUNDS |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-11T22%3A07%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=KRISZTIAN%20M&rft.date=1992-05-28&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EYU45890A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |