NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA
NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA, pronalazak se odnosi na derivate formule u kojoj, R1 i R2 predstavljaju H, alkil, alkenil, cikloalkil, N-alkilamino- ili N,N-dialkilaminoalkil, benzil, piridilmetil ili fenil eventualno supstituisane, R3 i R4 predstavljaju H, halogen, alkil, alkoksi, alkilt...
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| creator | DECERPRIT, J BELLEMIN, R DESCOURS, D |
| description | NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA, pronalazak se odnosi na derivate formule u kojoj, R1 i R2 predstavljaju H, alkil, alkenil, cikloalkil, N-alkilamino- ili N,N-dialkilaminoalkil, benzil, piridilmetil ili fenil eventualno supstituisane, R3 i R4 predstavljaju H, halogen, alkil, alkoksi, alkiltio, CF3, NO2, N-alkilamino ili N,N-dialkilamino, benzil ili fenil eventualno supstituisane, R5 predstavlja H, alkil, cikloalkil ili benzil eventualno supstituisane, R6 označava radikal alkila, fenila ili heterocilila eventualno supstituisane, Z označava biradikale:-(CH2)n-C(R7R8)-(CH2)p-, -CH=CH-C(R7R8)-u kojima n=0-2, p=0-2 i n+p-2, R7 i R8 predstavljaju H, alkil, alkenil, cikloalkil, N-alkilamino, N,N-dialkilamino, N-alkilamino- ili N,N-dialkilaminoalkil, benzil ili fenil koji mogu da budu supstituisani, ili formiraju zajedno lance polimetilena ili oksi-, tia- ili aminopolimetilena, kao na njihove tautomerne oblike, postupke za njihovo dobijanje i primenu kao lekova hipolipidemianta, anti-arteroskleroznih i antidijabetičnih.
The invention relates to indole derivatives of formula 1, 1 in which: R1 and R2 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl, pyridylmethyl or phenyl, optionally substituted, R3 and R4 represent H, halogen, alkyl, alkoxy, alkylthio, CF3, NO2, N-alkylamino or N,N-dialkylamino, benzyl or phenyl, optionally substituted, R5 represents H, alkyl, cycloalkyl or optionally substituted benzyl, R6 denotes an alkyl, phenyl or heterocyclic radical, optionally substituted, Z denotes the bivalent radicals -(CH2)n-C(R7R8)-(CH2)p-, -CH=CH-C(R7R8)- in which n=0-2, p=0-2 and n+p |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_YU30592A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>YU30592A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_YU30592A3</originalsourceid><addsrcrecordid>eNrjZND08w_zVHBxDfIMcwzxVPD0c_H3cVTwVAjwDw4JDXAGSvk7eXo5-nk58jCwpiXmFKfyQmluBlk31xBnD93Ugvz41OKCxOTUvNSS-MhQYwNTSyNHY0LyABUgItU</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA</title><source>esp@cenet</source><creator>DECERPRIT, J ; BELLEMIN, R ; DESCOURS, D</creator><creatorcontrib>DECERPRIT, J ; BELLEMIN, R ; DESCOURS, D</creatorcontrib><description>NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA, pronalazak se odnosi na derivate formule u kojoj, R1 i R2 predstavljaju H, alkil, alkenil, cikloalkil, N-alkilamino- ili N,N-dialkilaminoalkil, benzil, piridilmetil ili fenil eventualno supstituisane, R3 i R4 predstavljaju H, halogen, alkil, alkoksi, alkiltio, CF3, NO2, N-alkilamino ili N,N-dialkilamino, benzil ili fenil eventualno supstituisane, R5 predstavlja H, alkil, cikloalkil ili benzil eventualno supstituisane, R6 označava radikal alkila, fenila ili heterocilila eventualno supstituisane, Z označava biradikale:-(CH2)n-C(R7R8)-(CH2)p-, -CH=CH-C(R7R8)-u kojima n=0-2, p=0-2 i n+p-2, R7 i R8 predstavljaju H, alkil, alkenil, cikloalkil, N-alkilamino, N,N-dialkilamino, N-alkilamino- ili N,N-dialkilaminoalkil, benzil ili fenil koji mogu da budu supstituisani, ili formiraju zajedno lance polimetilena ili oksi-, tia- ili aminopolimetilena, kao na njihove tautomerne oblike, postupke za njihovo dobijanje i primenu kao lekova hipolipidemianta, anti-arteroskleroznih i antidijabetičnih.
The invention relates to indole derivatives of formula 1, 1 in which: R1 and R2 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl, pyridylmethyl or phenyl, optionally substituted, R3 and R4 represent H, halogen, alkyl, alkoxy, alkylthio, CF3, NO2, N-alkylamino or N,N-dialkylamino, benzyl or phenyl, optionally substituted, R5 represents H, alkyl, cycloalkyl or optionally substituted benzyl, R6 denotes an alkyl, phenyl or heterocyclic radical, optionally substituted, Z denotes the bivalent radicals -(CH2)n-C(R7R8)-(CH2)p-, -CH=CH-C(R7R8)- in which n=0-2, p=0-2 and n+p</=2, R7 and R8 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino, N,N-dialkylamino, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl or phenyl, where appropriate substituted, or together form polymethylene or oxa-, thia- or azapolymethylene chains, as well as their tautomeric forms, to processes for preparing them and to their application as hypolipidaemic, antiatheromatous and antidiabetic pharmaceutical products.</description><language>eng</language><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS ; CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1994</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19941228&DB=EPODOC&CC=YU&NR=30592A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19941228&DB=EPODOC&CC=YU&NR=30592A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>DECERPRIT, J</creatorcontrib><creatorcontrib>BELLEMIN, R</creatorcontrib><creatorcontrib>DESCOURS, D</creatorcontrib><title>NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA</title><description>NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA, pronalazak se odnosi na derivate formule u kojoj, R1 i R2 predstavljaju H, alkil, alkenil, cikloalkil, N-alkilamino- ili N,N-dialkilaminoalkil, benzil, piridilmetil ili fenil eventualno supstituisane, R3 i R4 predstavljaju H, halogen, alkil, alkoksi, alkiltio, CF3, NO2, N-alkilamino ili N,N-dialkilamino, benzil ili fenil eventualno supstituisane, R5 predstavlja H, alkil, cikloalkil ili benzil eventualno supstituisane, R6 označava radikal alkila, fenila ili heterocilila eventualno supstituisane, Z označava biradikale:-(CH2)n-C(R7R8)-(CH2)p-, -CH=CH-C(R7R8)-u kojima n=0-2, p=0-2 i n+p-2, R7 i R8 predstavljaju H, alkil, alkenil, cikloalkil, N-alkilamino, N,N-dialkilamino, N-alkilamino- ili N,N-dialkilaminoalkil, benzil ili fenil koji mogu da budu supstituisani, ili formiraju zajedno lance polimetilena ili oksi-, tia- ili aminopolimetilena, kao na njihove tautomerne oblike, postupke za njihovo dobijanje i primenu kao lekova hipolipidemianta, anti-arteroskleroznih i antidijabetičnih.
The invention relates to indole derivatives of formula 1, 1 in which: R1 and R2 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl, pyridylmethyl or phenyl, optionally substituted, R3 and R4 represent H, halogen, alkyl, alkoxy, alkylthio, CF3, NO2, N-alkylamino or N,N-dialkylamino, benzyl or phenyl, optionally substituted, R5 represents H, alkyl, cycloalkyl or optionally substituted benzyl, R6 denotes an alkyl, phenyl or heterocyclic radical, optionally substituted, Z denotes the bivalent radicals -(CH2)n-C(R7R8)-(CH2)p-, -CH=CH-C(R7R8)- in which n=0-2, p=0-2 and n+p</=2, R7 and R8 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino, N,N-dialkylamino, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl or phenyl, where appropriate substituted, or together form polymethylene or oxa-, thia- or azapolymethylene chains, as well as their tautomeric forms, to processes for preparing them and to their application as hypolipidaemic, antiatheromatous and antidiabetic pharmaceutical products.</description><subject>ACYCLIC OR CARBOCYCLIC COMPOUNDS</subject><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1994</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZND08w_zVHBxDfIMcwzxVPD0c_H3cVTwVAjwDw4JDXAGSvk7eXo5-nk58jCwpiXmFKfyQmluBlk31xBnD93Ugvz41OKCxOTUvNSS-MhQYwNTSyNHY0LyABUgItU</recordid><startdate>19941228</startdate><enddate>19941228</enddate><creator>DECERPRIT, J</creator><creator>BELLEMIN, R</creator><creator>DESCOURS, D</creator><scope>EVB</scope></search><sort><creationdate>19941228</creationdate><title>NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA</title><author>DECERPRIT, J ; BELLEMIN, R ; DESCOURS, D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_YU30592A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1994</creationdate><topic>ACYCLIC OR CARBOCYCLIC COMPOUNDS</topic><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>DECERPRIT, J</creatorcontrib><creatorcontrib>BELLEMIN, R</creatorcontrib><creatorcontrib>DESCOURS, D</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>DECERPRIT, J</au><au>BELLEMIN, R</au><au>DESCOURS, D</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA</title><date>1994-12-28</date><risdate>1994</risdate><abstract>NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA, pronalazak se odnosi na derivate formule u kojoj, R1 i R2 predstavljaju H, alkil, alkenil, cikloalkil, N-alkilamino- ili N,N-dialkilaminoalkil, benzil, piridilmetil ili fenil eventualno supstituisane, R3 i R4 predstavljaju H, halogen, alkil, alkoksi, alkiltio, CF3, NO2, N-alkilamino ili N,N-dialkilamino, benzil ili fenil eventualno supstituisane, R5 predstavlja H, alkil, cikloalkil ili benzil eventualno supstituisane, R6 označava radikal alkila, fenila ili heterocilila eventualno supstituisane, Z označava biradikale:-(CH2)n-C(R7R8)-(CH2)p-, -CH=CH-C(R7R8)-u kojima n=0-2, p=0-2 i n+p-2, R7 i R8 predstavljaju H, alkil, alkenil, cikloalkil, N-alkilamino, N,N-dialkilamino, N-alkilamino- ili N,N-dialkilaminoalkil, benzil ili fenil koji mogu da budu supstituisani, ili formiraju zajedno lance polimetilena ili oksi-, tia- ili aminopolimetilena, kao na njihove tautomerne oblike, postupke za njihovo dobijanje i primenu kao lekova hipolipidemianta, anti-arteroskleroznih i antidijabetičnih.
The invention relates to indole derivatives of formula 1, 1 in which: R1 and R2 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl, pyridylmethyl or phenyl, optionally substituted, R3 and R4 represent H, halogen, alkyl, alkoxy, alkylthio, CF3, NO2, N-alkylamino or N,N-dialkylamino, benzyl or phenyl, optionally substituted, R5 represents H, alkyl, cycloalkyl or optionally substituted benzyl, R6 denotes an alkyl, phenyl or heterocyclic radical, optionally substituted, Z denotes the bivalent radicals -(CH2)n-C(R7R8)-(CH2)p-, -CH=CH-C(R7R8)- in which n=0-2, p=0-2 and n+p</=2, R7 and R8 represent H, alkyl, alkenyl, cycloalkyl, N-alkylamino, N,N-dialkylamino, N-alkylamino- or N,N-dialkylaminoalkyl, benzyl or phenyl, where appropriate substituted, or together form polymethylene or oxa-, thia- or azapolymethylene chains, as well as their tautomeric forms, to processes for preparing them and to their application as hypolipidaemic, antiatheromatous and antidiabetic pharmaceutical products.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | NOVI DERIVATI INDOLA I POSTUPCI DOBIJANJA |
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