DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA
DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA, opisani su derivati imidazopiridina, jedinjenja formule; u kojoj X je CH ili N; Z je CH=CH ili S; A je CH2CH2, CH=CH, CH(OH)CH2, ili COCH2; B je direktna veza ili -CH2-, -CH(CH3)- ili -C(...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Patent |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | BASS, R.J ALKER, D COOPER, K |
| description | DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA, opisani su derivati imidazopiridina, jedinjenja formule; u kojoj X je CH ili N; Z je CH=CH ili S; A je CH2CH2, CH=CH, CH(OH)CH2, ili COCH2; B je direktna veza ili -CH2-, -CH(CH3)- ili -C(CH3)2-, ili kada Z je CH=CH, B može obrazovati kondenzovan ciklopentanov prsten vezan na benzenov prsten; Y kompletira kondenzovan benzo ili tienil prsten koji je po potrebi supstituisan sa halo ili C1-C4 alkil; n je 0, 1 ili 2; i m je 0 ili 1. Takodje je opisan postupak za dobijanje ovih derivata imidazopiridina koji obuhvata reakciju derivata piperidina formule (II) sa kiselinom formule (III) ili njenim aktiviranim derivatom: gde su X, Y, Z, A, B, n kao što je prethodno definisano.
PCT No. PCT/EP92/00163 Sec. 371 Date Jul. 12, 1993 Sec. 102(e) Date Jul. 12, 1993 PCT Filed Jan. 24, 1992 PCT Pub. No. WO92/14734 PCT Pub. Date Sep. 3, 1992.Compounds of formula (1), wherein X is CH or N; Z is CH=CH or S; A is CH2CH2, CH=CH, CH(OH)CH2, or COCH2; B is a direct link or -CH2-, -CH(CH3)- or -C(CH3)2-; or when Z is CH=CH, B may form a cyclopentane ring fused to the attached benzene ring; Y completes a fused benzo or thienyl ring which is optionally substituted by halo or C1-C4alkyl; n is 0, 1 or 2; and m is 0 or 1; are antagonists of both PAF and histamine H1 having utility in the treatment of allergic inflammatory conditions such as allergic rhinitis. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_YU14392A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>YU14392A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_YU14392A3</originalsourceid><addsrcrecordid>eNrjZChwcQ3yDHMM8VTw9PV0cYzyD_AM8nTx9HPUUQjwDw4JDXD0VohyVHDxd_L0cvTzclUI9nU9usBRIdhRwc_L09dRwROHOqi5jujm8jCwpiXmFKfyQmluBlk31xBnD93Ugvz41OKCxOTUvNSS-MhQQxNjSyNHY0LyAJkFNyQ</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA</title><source>esp@cenet</source><creator>BASS, R.J ; ALKER, D ; COOPER, K</creator><creatorcontrib>BASS, R.J ; ALKER, D ; COOPER, K</creatorcontrib><description>DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA, opisani su derivati imidazopiridina, jedinjenja formule; u kojoj X je CH ili N; Z je CH=CH ili S; A je CH2CH2, CH=CH, CH(OH)CH2, ili COCH2; B je direktna veza ili -CH2-, -CH(CH3)- ili -C(CH3)2-, ili kada Z je CH=CH, B može obrazovati kondenzovan ciklopentanov prsten vezan na benzenov prsten; Y kompletira kondenzovan benzo ili tienil prsten koji je po potrebi supstituisan sa halo ili C1-C4 alkil; n je 0, 1 ili 2; i m je 0 ili 1. Takodje je opisan postupak za dobijanje ovih derivata imidazopiridina koji obuhvata reakciju derivata piperidina formule (II) sa kiselinom formule (III) ili njenim aktiviranim derivatom: gde su X, Y, Z, A, B, n kao što je prethodno definisano.
PCT No. PCT/EP92/00163 Sec. 371 Date Jul. 12, 1993 Sec. 102(e) Date Jul. 12, 1993 PCT Filed Jan. 24, 1992 PCT Pub. No. WO92/14734 PCT Pub. Date Sep. 3, 1992.Compounds of formula (1), wherein X is CH or N; Z is CH=CH or S; A is CH2CH2, CH=CH, CH(OH)CH2, or COCH2; B is a direct link or -CH2-, -CH(CH3)- or -C(CH3)2-; or when Z is CH=CH, B may form a cyclopentane ring fused to the attached benzene ring; Y completes a fused benzo or thienyl ring which is optionally substituted by halo or C1-C4alkyl; n is 0, 1 or 2; and m is 0 or 1; are antagonists of both PAF and histamine H1 having utility in the treatment of allergic inflammatory conditions such as allergic rhinitis.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>1994</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19941115&DB=EPODOC&CC=YU&NR=14392A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19941115&DB=EPODOC&CC=YU&NR=14392A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BASS, R.J</creatorcontrib><creatorcontrib>ALKER, D</creatorcontrib><creatorcontrib>COOPER, K</creatorcontrib><title>DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA</title><description>DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA, opisani su derivati imidazopiridina, jedinjenja formule; u kojoj X je CH ili N; Z je CH=CH ili S; A je CH2CH2, CH=CH, CH(OH)CH2, ili COCH2; B je direktna veza ili -CH2-, -CH(CH3)- ili -C(CH3)2-, ili kada Z je CH=CH, B može obrazovati kondenzovan ciklopentanov prsten vezan na benzenov prsten; Y kompletira kondenzovan benzo ili tienil prsten koji je po potrebi supstituisan sa halo ili C1-C4 alkil; n je 0, 1 ili 2; i m je 0 ili 1. Takodje je opisan postupak za dobijanje ovih derivata imidazopiridina koji obuhvata reakciju derivata piperidina formule (II) sa kiselinom formule (III) ili njenim aktiviranim derivatom: gde su X, Y, Z, A, B, n kao što je prethodno definisano.
PCT No. PCT/EP92/00163 Sec. 371 Date Jul. 12, 1993 Sec. 102(e) Date Jul. 12, 1993 PCT Filed Jan. 24, 1992 PCT Pub. No. WO92/14734 PCT Pub. Date Sep. 3, 1992.Compounds of formula (1), wherein X is CH or N; Z is CH=CH or S; A is CH2CH2, CH=CH, CH(OH)CH2, or COCH2; B is a direct link or -CH2-, -CH(CH3)- or -C(CH3)2-; or when Z is CH=CH, B may form a cyclopentane ring fused to the attached benzene ring; Y completes a fused benzo or thienyl ring which is optionally substituted by halo or C1-C4alkyl; n is 0, 1 or 2; and m is 0 or 1; are antagonists of both PAF and histamine H1 having utility in the treatment of allergic inflammatory conditions such as allergic rhinitis.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1994</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZChwcQ3yDHMM8VTw9PV0cYzyD_AM8nTx9HPUUQjwDw4JDXD0VohyVHDxd_L0cvTzclUI9nU9usBRIdhRwc_L09dRwROHOqi5jujm8jCwpiXmFKfyQmluBlk31xBnD93Ugvz41OKCxOTUvNSS-MhQQxNjSyNHY0LyAJkFNyQ</recordid><startdate>19941115</startdate><enddate>19941115</enddate><creator>BASS, R.J</creator><creator>ALKER, D</creator><creator>COOPER, K</creator><scope>EVB</scope></search><sort><creationdate>19941115</creationdate><title>DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA</title><author>BASS, R.J ; ALKER, D ; COOPER, K</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_YU14392A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1994</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BASS, R.J</creatorcontrib><creatorcontrib>ALKER, D</creatorcontrib><creatorcontrib>COOPER, K</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BASS, R.J</au><au>ALKER, D</au><au>COOPER, K</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA</title><date>1994-11-15</date><risdate>1994</risdate><abstract>DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA, opisani su derivati imidazopiridina, jedinjenja formule; u kojoj X je CH ili N; Z je CH=CH ili S; A je CH2CH2, CH=CH, CH(OH)CH2, ili COCH2; B je direktna veza ili -CH2-, -CH(CH3)- ili -C(CH3)2-, ili kada Z je CH=CH, B može obrazovati kondenzovan ciklopentanov prsten vezan na benzenov prsten; Y kompletira kondenzovan benzo ili tienil prsten koji je po potrebi supstituisan sa halo ili C1-C4 alkil; n je 0, 1 ili 2; i m je 0 ili 1. Takodje je opisan postupak za dobijanje ovih derivata imidazopiridina koji obuhvata reakciju derivata piperidina formule (II) sa kiselinom formule (III) ili njenim aktiviranim derivatom: gde su X, Y, Z, A, B, n kao što je prethodno definisano.
PCT No. PCT/EP92/00163 Sec. 371 Date Jul. 12, 1993 Sec. 102(e) Date Jul. 12, 1993 PCT Filed Jan. 24, 1992 PCT Pub. No. WO92/14734 PCT Pub. Date Sep. 3, 1992.Compounds of formula (1), wherein X is CH or N; Z is CH=CH or S; A is CH2CH2, CH=CH, CH(OH)CH2, or COCH2; B is a direct link or -CH2-, -CH(CH3)- or -C(CH3)2-; or when Z is CH=CH, B may form a cyclopentane ring fused to the attached benzene ring; Y completes a fused benzo or thienyl ring which is optionally substituted by halo or C1-C4alkyl; n is 0, 1 or 2; and m is 0 or 1; are antagonists of both PAF and histamine H1 having utility in the treatment of allergic inflammatory conditions such as allergic rhinitis.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng |
| recordid | cdi_epo_espacenet_YU14392A |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-31T22%3A49%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BASS,%20R.J&rft.date=1994-11-15&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EYU14392A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |