PROCESS FOR OBTAINING A WATER SOLUBLE LYSINE OR ARGININE SALT OF N-(2-PYRIDYL)-2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-2-CARBOXAMIDE 1,1-DIOXIDE
The water-soluble lysine and arginine salts of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide have been prepared. These novel salts are useful in therapy as non-steroidal anti-arthritic agents, especially when administered by the parenteral route. Methods for prepari...
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| creator | LOMBARDINO J.G |
| description | The water-soluble lysine and arginine salts of N-(2-pyridyl)-2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide have been prepared. These novel salts are useful in therapy as non-steroidal anti-arthritic agents, especially when administered by the parenteral route. Methods for preparing these salts from the corresponding acidic starting material and the appropriate amine base are provided. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY |
| title | PROCESS FOR OBTAINING A WATER SOLUBLE LYSINE OR ARGININE SALT OF N-(2-PYRIDYL)-2-METHYL-4-HYDROXY-2H-1,2-BENZOTHIAZINE-2-CARBOXAMIDE 1,1-DIOXIDE |
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