USE OF 3'-AZIDO-2',3'-DIDEOXYURIDINE IN COMBINATION WITH FURTHER ANTI-HIV DRUGS FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF HIV

It has been discovered that 3'-azido-2',3'-dideoxyuridine (CS-87) induces a transient mutation in HIV-1 at the 70th codon (K to R, i.e., lysine to arginine) of the reverse transcriptase region of the virus. Based on this discovery, a method and composition for treating HIV is provided...

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Bibliographische Detailangaben
Hauptverfasser: MYERS, MAUREEN, W, SCHINAZI, RAYMOND, BRYANT, MARTIN, L
Format: Patent
Sprache:eng ; fre
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