CELLULAR PROTEINS WHICH MEDIATE HERPESVIRUS ENTRY

A cellular herpesvirus entry protein, or a mutant, a homolog, a derivative, a variant or a biologically active fragment thereof, suspended in a pharmaceutically active carrier in an amount effective to inhibit entry of an alphaherpesvirus into a cell, wherein the cellular herpesvirus entry protein i...

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Hauptverfasser: WHITBECK, CHARLES, J, MARTINEZ, WANDA, M, COHEN, GARY, H, SPEAR, PATRICIA, G, WARNER, MORGYN, S, GERAGHTY, ROBERT, G, MONGTOMERY, REBECCA, I, KRUMMENACHER, CLAUDE, EISENBERG, ROSELYN, J
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creator WHITBECK, CHARLES, J
MARTINEZ, WANDA, M
COHEN, GARY, H
SPEAR, PATRICIA, G
WARNER, MORGYN, S
GERAGHTY, ROBERT, G
MONGTOMERY, REBECCA, I
KRUMMENACHER, CLAUDE
EISENBERG, ROSELYN, J
description A cellular herpesvirus entry protein, or a mutant, a homolog, a derivative, a variant or a biologically active fragment thereof, suspended in a pharmaceutically active carrier in an amount effective to inhibit entry of an alphaherpesvirus into a cell, wherein the cellular herpesvirus entry protein is a member of the immunoglobulin superfamily, is provided and method of use thereof. L'invention concerne une protéine cellulaire assurant la médiation de l'entrée du virus herpétique. Il peut également s'agir d'un mutant, d'un homologue, d'un dérivé, d'un variant ou d'un fragment biologiquement actif de cette protéine. On met ladite protéine en suspension dans un vecteur pharmaceutiquement actif, en quantité suffisamment efficace pour inhiber l'entrée d'un virus herpétique alpha dans une cellule. La protéine cellulaire assurant la médiation de l'entrée du virus herpétique est un membre de la superfamille de l'immunoglobuline. L'invention concerne également un procédé d'utilisation correspondant.
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language eng ; fre
recordid cdi_epo_espacenet_WO9963063A1
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title CELLULAR PROTEINS WHICH MEDIATE HERPESVIRUS ENTRY
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