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Peptides and peptidomimetics that inhibit binding of cytochrome C to a Bcl-2-related family member, for use in therapy of autoimmune diseases and cancer as well as in prevention of graft rejection in organ transplant patients, by administering either the peptide, its peptidomimetic or an expression...

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Bibliographische Detailangaben
Hauptverfasser:	KHARBANDA, SURENDER, M, KUFE, DONALD, W, NALIN, CARLO, M, SHARMA, SUSHIL, K
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	Peptides and peptidomimetics that inhibit binding of cytochrome C to a Bcl-2-related family member, for use in therapy of autoimmune diseases and cancer as well as in prevention of graft rejection in organ transplant patients, by administering either the peptide, its peptidomimetic or an expression vector encoding the peptide. Peptides et peptidomimétiques inhibant la liaison du cytochrome C à un membre de la famille apparentée à Bcl-2, à utiliser dans le traitement des maladies auto-immunes et du cancer ainsi que dans la prévention du rejet de greffon chez les patients transplantés, par l'administration du peptide, de son peptidomimétique ou d'un vecteur d'expression codant le peptide.