Antitussive drugs deliverd by partially coated ionexchange resins

Antitussive drugs deliverd by partially coated ionexchange resins

The present invention relates generally to a mixture of coated and non-coated sulfonic acid cation exchange resins (Amberlite IR69) cross-linked with about 8% divinyl benzene onto which dextromethorphan has been loaded. About 30% of the drug/resin complexes are coated with a mixture of ethyl cellulo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: RAMSAY, MICHAEL, P, SCHHEURER, HENRICH, WEN, BETTY, P, LAM, VINCENT, DOKUZOVIC, ZDRAVKO
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator RAMSAY, MICHAEL, P
SCHHEURER, HENRICH
WEN, BETTY, P
LAM, VINCENT
DOKUZOVIC, ZDRAVKO
description The present invention relates generally to a mixture of coated and non-coated sulfonic acid cation exchange resins (Amberlite IR69) cross-linked with about 8% divinyl benzene onto which dextromethorphan has been loaded. About 30% of the drug/resin complexes are coated with a mixture of ethyl cellulose or ethyl cellulose latexes with plasticizers and water dispersible polymers such as SURELEASE. The coating level is about 50% w/w drug. Coated and uncoated drug/resin complexes are loaded with drug to about 45% by weight drug/resin complex. The ratio of coated and uncoated drug/resin complexes is about 55/45. The particle sizes of the coated and uncoated drug/resin complexes is about 20 to about 300 and about 20 to about 250 microns, respectively.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_WO9827961A3</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>WO9827961A3</sourcerecordid><originalsourceid>FETCH-epo_espacenet_WO9827961A33</originalsourceid><addsrcrecordid>eNrjZHB0zCvJLCktLs4sS1VIKSpNL1ZISc0BcopSFJIqFQoSi0oyE3NyKhWS8xNLUlMUMvPzUiuSMxLz0lMVilKLM_OKeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJfLi_pYWRuaWZoaOxMRFKAP6-Mjc</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Antitussive drugs deliverd by partially coated ionexchange resins</title><source>esp@cenet</source><creator>RAMSAY, MICHAEL, P ; SCHHEURER, HENRICH ; WEN, BETTY, P ; LAM, VINCENT ; DOKUZOVIC, ZDRAVKO</creator><creatorcontrib>RAMSAY, MICHAEL, P ; SCHHEURER, HENRICH ; WEN, BETTY, P ; LAM, VINCENT ; DOKUZOVIC, ZDRAVKO</creatorcontrib><description>The present invention relates generally to a mixture of coated and non-coated sulfonic acid cation exchange resins (Amberlite IR69) cross-linked with about 8% divinyl benzene onto which dextromethorphan has been loaded. About 30% of the drug/resin complexes are coated with a mixture of ethyl cellulose or ethyl cellulose latexes with plasticizers and water dispersible polymers such as SURELEASE. The coating level is about 50% w/w drug. Coated and uncoated drug/resin complexes are loaded with drug to about 45% by weight drug/resin complex. The ratio of coated and uncoated drug/resin complexes is about 55/45. The particle sizes of the coated and uncoated drug/resin complexes is about 20 to about 300 and about 20 to about 250 microns, respectively.</description><edition>6</edition><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1998</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19980911&amp;DB=EPODOC&amp;CC=WO&amp;NR=9827961A3$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19980911&amp;DB=EPODOC&amp;CC=WO&amp;NR=9827961A3$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>RAMSAY, MICHAEL, P</creatorcontrib><creatorcontrib>SCHHEURER, HENRICH</creatorcontrib><creatorcontrib>WEN, BETTY, P</creatorcontrib><creatorcontrib>LAM, VINCENT</creatorcontrib><creatorcontrib>DOKUZOVIC, ZDRAVKO</creatorcontrib><title>Antitussive drugs deliverd by partially coated ionexchange resins</title><description>The present invention relates generally to a mixture of coated and non-coated sulfonic acid cation exchange resins (Amberlite IR69) cross-linked with about 8% divinyl benzene onto which dextromethorphan has been loaded. About 30% of the drug/resin complexes are coated with a mixture of ethyl cellulose or ethyl cellulose latexes with plasticizers and water dispersible polymers such as SURELEASE. The coating level is about 50% w/w drug. Coated and uncoated drug/resin complexes are loaded with drug to about 45% by weight drug/resin complex. The ratio of coated and uncoated drug/resin complexes is about 55/45. The particle sizes of the coated and uncoated drug/resin complexes is about 20 to about 300 and about 20 to about 250 microns, respectively.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1998</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHB0zCvJLCktLs4sS1VIKSpNL1ZISc0BcopSFJIqFQoSi0oyE3NyKhWS8xNLUlMUMvPzUiuSMxLz0lMVilKLM_OKeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJfLi_pYWRuaWZoaOxMRFKAP6-Mjc</recordid><startdate>19980911</startdate><enddate>19980911</enddate><creator>RAMSAY, MICHAEL, P</creator><creator>SCHHEURER, HENRICH</creator><creator>WEN, BETTY, P</creator><creator>LAM, VINCENT</creator><creator>DOKUZOVIC, ZDRAVKO</creator><scope>EVB</scope></search><sort><creationdate>19980911</creationdate><title>Antitussive drugs deliverd by partially coated ionexchange resins</title><author>RAMSAY, MICHAEL, P ; SCHHEURER, HENRICH ; WEN, BETTY, P ; LAM, VINCENT ; DOKUZOVIC, ZDRAVKO</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO9827961A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1998</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>RAMSAY, MICHAEL, P</creatorcontrib><creatorcontrib>SCHHEURER, HENRICH</creatorcontrib><creatorcontrib>WEN, BETTY, P</creatorcontrib><creatorcontrib>LAM, VINCENT</creatorcontrib><creatorcontrib>DOKUZOVIC, ZDRAVKO</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>RAMSAY, MICHAEL, P</au><au>SCHHEURER, HENRICH</au><au>WEN, BETTY, P</au><au>LAM, VINCENT</au><au>DOKUZOVIC, ZDRAVKO</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Antitussive drugs deliverd by partially coated ionexchange resins</title><date>1998-09-11</date><risdate>1998</risdate><abstract>The present invention relates generally to a mixture of coated and non-coated sulfonic acid cation exchange resins (Amberlite IR69) cross-linked with about 8% divinyl benzene onto which dextromethorphan has been loaded. About 30% of the drug/resin complexes are coated with a mixture of ethyl cellulose or ethyl cellulose latexes with plasticizers and water dispersible polymers such as SURELEASE. The coating level is about 50% w/w drug. Coated and uncoated drug/resin complexes are loaded with drug to about 45% by weight drug/resin complex. The ratio of coated and uncoated drug/resin complexes is about 55/45. The particle sizes of the coated and uncoated drug/resin complexes is about 20 to about 300 and about 20 to about 250 microns, respectively.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_WO9827961A3
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Antitussive drugs deliverd by partially coated ionexchange resins
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-04T13%3A20%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=RAMSAY,%20MICHAEL,%20P&rft.date=1998-09-11&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EWO9827961A3%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true