PROPOFOL NANODISPERSIONS

The invention relates to nanodispersions for the intravenous administration of the anaesthetic agent propofolum having lipophilic properties. The nanodispersion is prepared by adding propofolum to an aqueous solution of a partial fatty acid ester of polyoxyethylene sorbitan at low concentrations fol...

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description The invention relates to nanodispersions for the intravenous administration of the anaesthetic agent propofolum having lipophilic properties. The nanodispersion is prepared by adding propofolum to an aqueous solution of a partial fatty acid ester of polyoxyethylene sorbitan at low concentrations followed by moderate stirring at room temperature or under moderate heating. La présente invention concerne des nanodispersions pour l'administration intraveineuse de propofolum, un agent anesthésique doté de propriétés lipophiles. La nanodispersion se prépare par adjonction de propofolum dans une solution aqueuse d'ester partiel d'acide gras de sorbitane de polyoxyéthylène à basse concentration puis agitation modérée à température ambiante ou sous l'effet d'un chauffage modéré.
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The nanodispersion is prepared by adding propofolum to an aqueous solution of a partial fatty acid ester of polyoxyethylene sorbitan at low concentrations followed by moderate stirring at room temperature or under moderate heating. La présente invention concerne des nanodispersions pour l'administration intraveineuse de propofolum, un agent anesthésique doté de propriétés lipophiles. La nanodispersion se prépare par adjonction de propofolum dans une solution aqueuse d'ester partiel d'acide gras de sorbitane de polyoxyéthylène à basse concentration puis agitation modérée à température ambiante ou sous l'effet d'un chauffage modéré.</description><edition>6</edition><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>1997</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19970327&amp;DB=EPODOC&amp;CC=WO&amp;NR=9710814A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19970327&amp;DB=EPODOC&amp;CC=WO&amp;NR=9710814A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>WEDER, HANS, GEORG</creatorcontrib><title>PROPOFOL NANODISPERSIONS</title><description>The invention relates to nanodispersions for the intravenous administration of the anaesthetic agent propofolum having lipophilic properties. 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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title PROPOFOL NANODISPERSIONS
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