METHOD FOR DETECTING A MUTATION INVOLVED IN ALZHEIMER'S DISEASE AND NUCLEOTIDE SEQUENCES FOR IMPLEMENTING SAME
Method for detecting, in a DNA preparation, a mutation involved in Alzheimer's disease, by determining the presence, in the apolipoprotein E gene, of one of the following nucleotide sequences, designated as SEQ ID N DEG 1, SEQ ID N DEG 3 and SEQ ID N DEG 5: SEQ ID N DEG 1: TGC GGC CGC; SEQ ID N...
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| creator | LUCOTTE, GERARD REVEILLEAU, STEPHANE |
| description | Method for detecting, in a DNA preparation, a mutation involved in Alzheimer's disease, by determining the presence, in the apolipoprotein E gene, of one of the following nucleotide sequences, designated as SEQ ID N DEG 1, SEQ ID N DEG 3 and SEQ ID N DEG 5: SEQ ID N DEG 1: TGC GGC CGC; SEQ ID N DEG 3: TGC GAC CGC; SEQ ID N DEG 5: CGC GAC CGC. The determination is achieved by polymerase chain reaction (PCR) or sequencing techniques.
Procédé de détection, dans une préparation d'ADN, d'une mutation intervenant dans la maladie d'Alzheimer caractérisé en ce que l'on détermine la présence, dans le gène de l'apolipoprotéine E, d'une des séquences nucléotidiques SEQ ID N DEG 1, SEQ ID N DEG 3 ou SEQ ID N DEG 5 suivantes: SEQ ID N DEG 1: TGC GGC CGC; SEQ ID N DEG 3: TGC GAC CGC; SEQ ID N DEG 5: CGC GAC CGC. Cette détermination peut être effectuée par amplification en chaîne par polymérase (PCR) ou par séquençage. |
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Procédé de détection, dans une préparation d'ADN, d'une mutation intervenant dans la maladie d'Alzheimer caractérisé en ce que l'on détermine la présence, dans le gène de l'apolipoprotéine E, d'une des séquences nucléotidiques SEQ ID N DEG 1, SEQ ID N DEG 3 ou SEQ ID N DEG 5 suivantes: SEQ ID N DEG 1: TGC GGC CGC; SEQ ID N DEG 3: TGC GAC CGC; SEQ ID N DEG 5: CGC GAC CGC. Cette détermination peut être effectuée par amplification en chaîne par polymérase (PCR) ou par séquençage.</description><edition>6</edition><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960822&DB=EPODOC&CC=WO&NR=9625517A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960822&DB=EPODOC&CC=WO&NR=9625517A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LUCOTTE, GERARD</creatorcontrib><creatorcontrib>REVEILLEAU, STEPHANE</creatorcontrib><title>METHOD FOR DETECTING A MUTATION INVOLVED IN ALZHEIMER'S DISEASE AND NUCLEOTIDE SEQUENCES FOR IMPLEMENTING SAME</title><description>Method for detecting, in a DNA preparation, a mutation involved in Alzheimer's disease, by determining the presence, in the apolipoprotein E gene, of one of the following nucleotide sequences, designated as SEQ ID N DEG 1, SEQ ID N DEG 3 and SEQ ID N DEG 5: SEQ ID N DEG 1: TGC GGC CGC; SEQ ID N DEG 3: TGC GAC CGC; SEQ ID N DEG 5: CGC GAC CGC. The determination is achieved by polymerase chain reaction (PCR) or sequencing techniques.
Procédé de détection, dans une préparation d'ADN, d'une mutation intervenant dans la maladie d'Alzheimer caractérisé en ce que l'on détermine la présence, dans le gène de l'apolipoprotéine E, d'une des séquences nucléotidiques SEQ ID N DEG 1, SEQ ID N DEG 3 ou SEQ ID N DEG 5 suivantes: SEQ ID N DEG 1: TGC GGC CGC; SEQ ID N DEG 3: TGC GAC CGC; SEQ ID N DEG 5: CGC GAC CGC. Cette détermination peut être effectuée par amplification en chaîne par polymérase (PCR) ou par séquençage.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>ENZYMOLOGY</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1996</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjL0KwjAURrs4iPoOd3NyqFLFMSRf7YX8aJNUcClF4iS1UN8fpfgATucMhzPPeoNQOUWlq0khQAa2JxJkYhCBnSW2jdMN1FdI6FsFNqjXnhR7CA8SVpGNUsMFViCPS4SV8NORzVnDwE5TLwyW2ezRPce0-nGRUYkgq00aXm0ah-6e-vRur-643xZFfhD57o_kA-kVNu4</recordid><startdate>19960822</startdate><enddate>19960822</enddate><creator>LUCOTTE, GERARD</creator><creator>REVEILLEAU, STEPHANE</creator><scope>EVB</scope></search><sort><creationdate>19960822</creationdate><title>METHOD FOR DETECTING A MUTATION INVOLVED IN ALZHEIMER'S DISEASE AND NUCLEOTIDE SEQUENCES FOR IMPLEMENTING SAME</title><author>LUCOTTE, GERARD ; REVEILLEAU, STEPHANE</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO9625517A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>1996</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>ENZYMOLOGY</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>LUCOTTE, GERARD</creatorcontrib><creatorcontrib>REVEILLEAU, STEPHANE</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>LUCOTTE, GERARD</au><au>REVEILLEAU, STEPHANE</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHOD FOR DETECTING A MUTATION INVOLVED IN ALZHEIMER'S DISEASE AND NUCLEOTIDE SEQUENCES FOR IMPLEMENTING SAME</title><date>1996-08-22</date><risdate>1996</risdate><abstract>Method for detecting, in a DNA preparation, a mutation involved in Alzheimer's disease, by determining the presence, in the apolipoprotein E gene, of one of the following nucleotide sequences, designated as SEQ ID N DEG 1, SEQ ID N DEG 3 and SEQ ID N DEG 5: SEQ ID N DEG 1: TGC GGC CGC; SEQ ID N DEG 3: TGC GAC CGC; SEQ ID N DEG 5: CGC GAC CGC. The determination is achieved by polymerase chain reaction (PCR) or sequencing techniques.
Procédé de détection, dans une préparation d'ADN, d'une mutation intervenant dans la maladie d'Alzheimer caractérisé en ce que l'on détermine la présence, dans le gène de l'apolipoprotéine E, d'une des séquences nucléotidiques SEQ ID N DEG 1, SEQ ID N DEG 3 ou SEQ ID N DEG 5 suivantes: SEQ ID N DEG 1: TGC GGC CGC; SEQ ID N DEG 3: TGC GAC CGC; SEQ ID N DEG 5: CGC GAC CGC. Cette détermination peut être effectuée par amplification en chaîne par polymérase (PCR) ou par séquençage.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | METHOD FOR DETECTING A MUTATION INVOLVED IN ALZHEIMER'S DISEASE AND NUCLEOTIDE SEQUENCES FOR IMPLEMENTING SAME |
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