SUSTANCE WITH ANTIVIRAL ACTIVITY
A phosphorothioate oligodeoxyribonucleotide which has 5 to 30 base units and contains at least one base sequence (wherein G represents guanine and X represents any of adenine, thymine, guanine and cytosine) and wherein the linkage between the nucleosides is a phosphorothioate linkage, a salt thereo...
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| creator | IWATANI, WAKAO TAMURA, NOBUYA SHOJI, YOKO SHIMADA, JINGORO MIZUSHIMA, YUTAKA |
| description | A phosphorothioate oligodeoxyribonucleotide which has 5 to 30 base units and contains at least one base sequence (wherein G represents guanine and X represents any of adenine, thymine, guanine and cytosine) and wherein the linkage between the nucleosides is a phosphorothioate linkage, a salt thereof and chemical modifications thereof; and an antiviral agent containing the same. This compound has a high antiviral activity against herpes simplex virus and human immunodeficiency virus (HIV) and is useful for treating or preventing various viral infections.
Oligodésoxyribonucléotide de phosphorothioate qui possède 5 à 30 unités de base et contient au moins une séquence de base (dans laquelle G représente guanine et X représente adénine, thymine, guanine ou cytosine) et dans lequel la liaison entre les nucléosides est une liaison phosphorothioate, sel dudit oligodésoxyribonucléotide et modifications chimiques de ce dernier, ainsi qu'un agent antiviral contenant cet oligodésoxyribonucléotide. Ledit composé possède une forte activité antivirale contre le virus de l'herpès simplex et le virus de l'immunodéficience humain (VIH) et est utile pour traiter ou prévenir diverses infections virales. |
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Oligodésoxyribonucléotide de phosphorothioate qui possède 5 à 30 unités de base et contient au moins une séquence de base <5'>-GXGGG-<3'> (dans laquelle G représente guanine et X représente adénine, thymine, guanine ou cytosine) et dans lequel la liaison entre les nucléosides est une liaison phosphorothioate, sel dudit oligodésoxyribonucléotide et modifications chimiques de ce dernier, ainsi qu'un agent antiviral contenant cet oligodésoxyribonucléotide. Ledit composé possède une forte activité antivirale contre le virus de l'herpès simplex et le virus de l'immunodéficience humain (VIH) et est utile pour traiter ou prévenir diverses infections virales.</description><edition>6</edition><language>eng ; fre ; jpn</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>1996</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960208&DB=EPODOC&CC=WO&NR=9603500A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,309,781,886,25568,76551</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19960208&DB=EPODOC&CC=WO&NR=9603500A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>IWATANI, WAKAO</creatorcontrib><creatorcontrib>TAMURA, NOBUYA</creatorcontrib><creatorcontrib>SHOJI, YOKO</creatorcontrib><creatorcontrib>SHIMADA, JINGORO</creatorcontrib><creatorcontrib>MIZUSHIMA, YUTAKA</creatorcontrib><title>SUSTANCE WITH ANTIVIRAL ACTIVITY</title><description>A phosphorothioate oligodeoxyribonucleotide which has 5 to 30 base units and contains at least one base sequence <5'>-GXGGG-<3'> (wherein G represents guanine and X represents any of adenine, thymine, guanine and cytosine) and wherein the linkage between the nucleosides is a phosphorothioate linkage, a salt thereof and chemical modifications thereof; and an antiviral agent containing the same. This compound has a high antiviral activity against herpes simplex virus and human immunodeficiency virus (HIV) and is useful for treating or preventing various viral infections.
Oligodésoxyribonucléotide de phosphorothioate qui possède 5 à 30 unités de base et contient au moins une séquence de base <5'>-GXGGG-<3'> (dans laquelle G représente guanine et X représente adénine, thymine, guanine ou cytosine) et dans lequel la liaison entre les nucléosides est une liaison phosphorothioate, sel dudit oligodésoxyribonucléotide et modifications chimiques de ce dernier, ainsi qu'un agent antiviral contenant cet oligodésoxyribonucléotide. Ledit composé possède une forte activité antivirale contre le virus de l'herpès simplex et le virus de l'immunodéficience humain (VIH) et est utile pour traiter ou prévenir diverses infections virales.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1996</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZFAIDg0OcfRzdlUI9wzxUHD0C_EM8wxy9FFwdAaxQiJ5GFjTEnOKU3mhNDeDgptriLOHbmpBfnxqcUFicmpeakl8uL-lmYGxqYGBo6ExEUoA0Lkh2A</recordid><startdate>19960208</startdate><enddate>19960208</enddate><creator>IWATANI, WAKAO</creator><creator>TAMURA, NOBUYA</creator><creator>SHOJI, YOKO</creator><creator>SHIMADA, JINGORO</creator><creator>MIZUSHIMA, YUTAKA</creator><scope>EVB</scope></search><sort><creationdate>19960208</creationdate><title>SUSTANCE WITH ANTIVIRAL ACTIVITY</title><author>IWATANI, WAKAO ; TAMURA, NOBUYA ; SHOJI, YOKO ; SHIMADA, JINGORO ; MIZUSHIMA, YUTAKA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO9603500A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre ; jpn</language><creationdate>1996</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>IWATANI, WAKAO</creatorcontrib><creatorcontrib>TAMURA, NOBUYA</creatorcontrib><creatorcontrib>SHOJI, YOKO</creatorcontrib><creatorcontrib>SHIMADA, JINGORO</creatorcontrib><creatorcontrib>MIZUSHIMA, YUTAKA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>IWATANI, WAKAO</au><au>TAMURA, NOBUYA</au><au>SHOJI, YOKO</au><au>SHIMADA, JINGORO</au><au>MIZUSHIMA, YUTAKA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SUSTANCE WITH ANTIVIRAL ACTIVITY</title><date>1996-02-08</date><risdate>1996</risdate><abstract>A phosphorothioate oligodeoxyribonucleotide which has 5 to 30 base units and contains at least one base sequence <5'>-GXGGG-<3'> (wherein G represents guanine and X represents any of adenine, thymine, guanine and cytosine) and wherein the linkage between the nucleosides is a phosphorothioate linkage, a salt thereof and chemical modifications thereof; and an antiviral agent containing the same. This compound has a high antiviral activity against herpes simplex virus and human immunodeficiency virus (HIV) and is useful for treating or preventing various viral infections.
Oligodésoxyribonucléotide de phosphorothioate qui possède 5 à 30 unités de base et contient au moins une séquence de base <5'>-GXGGG-<3'> (dans laquelle G représente guanine et X représente adénine, thymine, guanine ou cytosine) et dans lequel la liaison entre les nucléosides est une liaison phosphorothioate, sel dudit oligodésoxyribonucléotide et modifications chimiques de ce dernier, ainsi qu'un agent antiviral contenant cet oligodésoxyribonucléotide. Ledit composé possède une forte activité antivirale contre le virus de l'herpès simplex et le virus de l'immunodéficience humain (VIH) et est utile pour traiter ou prévenir diverses infections virales.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | SUSTANCE WITH ANTIVIRAL ACTIVITY |
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