IMMUNOASSAYS FOR PROSTATE SPECIFIC ANTIGEN
The present invention relates to the field of cancer immunoassay. Specifically, a new immunoassay method for prostate specific antigen (PSA) is presented. Also presented is a complex which resembles a complex of PSA and alpha -antichymotrypsin (ACT) that can be used as a calibrator or control in an...
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| creator | KING, CAROL, A O'MORCHOE, SUSAN, B DOWELL, BARRY, L ALEXANDER, DEBRA, B SMITH, ALLAN, H |
| description | The present invention relates to the field of cancer immunoassay. Specifically, a new immunoassay method for prostate specific antigen (PSA) is presented. Also presented is a complex which resembles a complex of PSA and alpha -antichymotrypsin (ACT) that can be used as a calibrator or control in an immunoassay for PSA. Further presented is a method for fractionating polyclonal antibodies, to PSA, into those which bind epitopes that are masked by the binding of PSA to ACT and those which do not bind such epitopes.
La présente invention concerne un immunodosage auquel on fait appel en cancérologie. De façon spécifique, un nouveau procédé d'immunodosage relatif à l'antigène spécifique de la prostate (PSA) est décrit. L'invention concerne également un complexe qui ressemble au complexe PSA et alpha -antichymotrypsine (ACT) qui peut être utilisé comme élément d'étalonnage ou témoin dans un immunodosage relatif au PSA. Est également décrit un procédé permettant de séparer, parmi des anticorps polyclonaux dirigés contre le PSA, ceux qui fixent des épitopes qui sont masqués par la liaison du PSA à l'ACT de ceux qui ne fixent pas de tels épitopes. |
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La présente invention concerne un immunodosage auquel on fait appel en cancérologie. De façon spécifique, un nouveau procédé d'immunodosage relatif à l'antigène spécifique de la prostate (PSA) est décrit. L'invention concerne également un complexe qui ressemble au complexe PSA et alpha -antichymotrypsine (ACT) qui peut être utilisé comme élément d'étalonnage ou témoin dans un immunodosage relatif au PSA. Est également décrit un procédé permettant de séparer, parmi des anticorps polyclonaux dirigés contre le PSA, ceux qui fixent des épitopes qui sont masqués par la liaison du PSA à l'ACT de ceux qui ne fixent pas de tels épitopes.</description><edition>6</edition><language>eng ; fre</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; TESTING</subject><creationdate>1995</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950706&DB=EPODOC&CC=WO&NR=9518381A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19950706&DB=EPODOC&CC=WO&NR=9518381A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KING, CAROL, A</creatorcontrib><creatorcontrib>O'MORCHOE, SUSAN, B</creatorcontrib><creatorcontrib>DOWELL, BARRY, L</creatorcontrib><creatorcontrib>ALEXANDER, DEBRA, B</creatorcontrib><creatorcontrib>SMITH, ALLAN, H</creatorcontrib><title>IMMUNOASSAYS FOR PROSTATE SPECIFIC ANTIGEN</title><description>The present invention relates to the field of cancer immunoassay. Specifically, a new immunoassay method for prostate specific antigen (PSA) is presented. Also presented is a complex which resembles a complex of PSA and alpha -antichymotrypsin (ACT) that can be used as a calibrator or control in an immunoassay for PSA. Further presented is a method for fractionating polyclonal antibodies, to PSA, into those which bind epitopes that are masked by the binding of PSA to ACT and those which do not bind such epitopes.
La présente invention concerne un immunodosage auquel on fait appel en cancérologie. De façon spécifique, un nouveau procédé d'immunodosage relatif à l'antigène spécifique de la prostate (PSA) est décrit. L'invention concerne également un complexe qui ressemble au complexe PSA et alpha -antichymotrypsine (ACT) qui peut être utilisé comme élément d'étalonnage ou témoin dans un immunodosage relatif au PSA. Est également décrit un procédé permettant de séparer, parmi des anticorps polyclonaux dirigés contre le PSA, ceux qui fixent des épitopes qui sont masqués par la liaison du PSA à l'ACT de ceux qui ne fixent pas de tels épitopes.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1995</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDy9PUN9fN3DA52jAxWcPMPUggI8g8OcQxxVQgOcHX2dPN0VnD0C_F0d_XjYWBNS8wpTuWF0twMCm6uIc4euqkF-fGpxQWJyal5qSXx4f6WpoYWxhaGjobGRCgBAC8QJK8</recordid><startdate>19950706</startdate><enddate>19950706</enddate><creator>KING, CAROL, A</creator><creator>O'MORCHOE, SUSAN, B</creator><creator>DOWELL, BARRY, L</creator><creator>ALEXANDER, DEBRA, B</creator><creator>SMITH, ALLAN, H</creator><scope>EVB</scope></search><sort><creationdate>19950706</creationdate><title>IMMUNOASSAYS FOR PROSTATE SPECIFIC ANTIGEN</title><author>KING, CAROL, A ; O'MORCHOE, SUSAN, B ; DOWELL, BARRY, L ; ALEXANDER, DEBRA, B ; SMITH, ALLAN, H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO9518381A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>1995</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>KING, CAROL, A</creatorcontrib><creatorcontrib>O'MORCHOE, SUSAN, B</creatorcontrib><creatorcontrib>DOWELL, BARRY, L</creatorcontrib><creatorcontrib>ALEXANDER, DEBRA, B</creatorcontrib><creatorcontrib>SMITH, ALLAN, H</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KING, CAROL, A</au><au>O'MORCHOE, SUSAN, B</au><au>DOWELL, BARRY, L</au><au>ALEXANDER, DEBRA, B</au><au>SMITH, ALLAN, H</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>IMMUNOASSAYS FOR PROSTATE SPECIFIC ANTIGEN</title><date>1995-07-06</date><risdate>1995</risdate><abstract>The present invention relates to the field of cancer immunoassay. Specifically, a new immunoassay method for prostate specific antigen (PSA) is presented. Also presented is a complex which resembles a complex of PSA and alpha -antichymotrypsin (ACT) that can be used as a calibrator or control in an immunoassay for PSA. Further presented is a method for fractionating polyclonal antibodies, to PSA, into those which bind epitopes that are masked by the binding of PSA to ACT and those which do not bind such epitopes.
La présente invention concerne un immunodosage auquel on fait appel en cancérologie. De façon spécifique, un nouveau procédé d'immunodosage relatif à l'antigène spécifique de la prostate (PSA) est décrit. L'invention concerne également un complexe qui ressemble au complexe PSA et alpha -antichymotrypsine (ACT) qui peut être utilisé comme élément d'étalonnage ou témoin dans un immunodosage relatif au PSA. Est également décrit un procédé permettant de séparer, parmi des anticorps polyclonaux dirigés contre le PSA, ceux qui fixent des épitopes qui sont masqués par la liaison du PSA à l'ACT de ceux qui ne fixent pas de tels épitopes.</abstract><edition>6</edition><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING |
| title | IMMUNOASSAYS FOR PROSTATE SPECIFIC ANTIGEN |
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