HOMOGENEOUS MEMBRANE LYTIC IMMUNOASSAY METHOD UTILIZING CONTACT SENSITIVE LIPOSOME FORMULATIONS

A contact sensitive liposome formulation, comprising from about 0.1 to about 99.9 mole percent of one or more inverted hexagonal phase forming lipids, said liposome stabilized in the bilayer phase with from about 0.1 to about 99.9 mole percent of one or more analyte independent amphipathic stabilize...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	HILLIS, LARRY, R, BABBITT, BRUCE, P
Format:	Patent
Sprache:	eng
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	A contact sensitive liposome formulation, comprising from about 0.1 to about 99.9 mole percent of one or more inverted hexagonal phase forming lipids, said liposome stabilized in the bilayer phase with from about 0.1 to about 99.9 mole percent of one or more analyte independent amphipathic stabilizer molecules or mixtures thereof, said liposome further comprising one or more targeting molecules on the surface thereof. Formulation de liposome sensible au contact comprenant environ 0,1 à environ 99,9 mole pourcent d'un ou de plusieurs lipides formant des phases hexagonales inversées, ledit liposome stabilisé dans la phase à deux couches comportant environ 0,1 à environ 99,9 pourcent en moles d'une ou de plusieurs molécules stabilisatrices amphipatiques indépendantes de l'analyte ou de mélanges de ces dernières, ledit liposome comprenant en outre une ou plusieurs molécules de ciblage sur sa surface.