PROCESS FOR 2-DEOXYGLUCOSIDES
The invention provides a process for the preparation of methyl tri-O-acetyl-2-deoxyglucoside by the reaction of tri-O-acetyl-D-glucal with methanol in the presence of hydrogen bromide or a source thereof. alpha -Methyl tri-O-acetyl-2-deoxyglucoside is especially useful as an intermediate in the prep...
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| creator | PITCHEN, PHILIPPE MIOSKOWSKI, CHARLES |
| description | The invention provides a process for the preparation of methyl tri-O-acetyl-2-deoxyglucoside by the reaction of tri-O-acetyl-D-glucal with methanol in the presence of hydrogen bromide or a source thereof. alpha -Methyl tri-O-acetyl-2-deoxyglucoside is especially useful as an intermediate in the preparation of pharmaceutically useful mevalonic acid derivatives.
Cette invention se rapporte à un procédé de préparation de tri-O-acétyle-2-désoxyglucoside de méthyle qui consiste à faire réagir du tri-O-acétyle-D-glucal avec du méthanol en présence de bromure d'hydrogène ou d'une source de bromure d'hydrogène. Le tri-O-acétyle-2-désoxyglucoside de méthyle-alpha est particulièrement utile comme élément intermédiaire dans la préparation de dérivés d'acide mévalonique. |
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Cette invention se rapporte à un procédé de préparation de tri-O-acétyle-2-désoxyglucoside de méthyle qui consiste à faire réagir du tri-O-acétyle-D-glucal avec du méthanol en présence de bromure d'hydrogène ou d'une source de bromure d'hydrogène. Le tri-O-acétyle-2-désoxyglucoside de méthyle-alpha est particulièrement utile comme élément intermédiaire dans la préparation de dérivés d'acide mévalonique.</description><language>eng</language><subject>CHEMISTRY ; DERIVATIVES THEREOF ; METALLURGY ; NUCLEIC ACIDS ; NUCLEOSIDES ; NUCLEOTIDES ; ORGANIC CHEMISTRY ; SUGARS</subject><creationdate>1991</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19911226&DB=EPODOC&CC=WO&NR=9119724A2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,778,883,25551,76302</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19911226&DB=EPODOC&CC=WO&NR=9119724A2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PITCHEN, PHILIPPE</creatorcontrib><creatorcontrib>MIOSKOWSKI, CHARLES</creatorcontrib><title>PROCESS FOR 2-DEOXYGLUCOSIDES</title><description>The invention provides a process for the preparation of methyl tri-O-acetyl-2-deoxyglucoside by the reaction of tri-O-acetyl-D-glucal with methanol in the presence of hydrogen bromide or a source thereof. alpha -Methyl tri-O-acetyl-2-deoxyglucoside is especially useful as an intermediate in the preparation of pharmaceutically useful mevalonic acid derivatives.
Cette invention se rapporte à un procédé de préparation de tri-O-acétyle-2-désoxyglucoside de méthyle qui consiste à faire réagir du tri-O-acétyle-D-glucal avec du méthanol en présence de bromure d'hydrogène ou d'une source de bromure d'hydrogène. Le tri-O-acétyle-2-désoxyglucoside de méthyle-alpha est particulièrement utile comme élément intermédiaire dans la préparation de dérivés d'acide mévalonique.</description><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1991</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJANCPJ3dg0OVnDzD1Iw0nVx9Y-IdPcJdfYP9nRxDeZhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfHh_paGhpbmRiaORsZEKAEAX6Ig8g</recordid><startdate>19911226</startdate><enddate>19911226</enddate><creator>PITCHEN, PHILIPPE</creator><creator>MIOSKOWSKI, CHARLES</creator><scope>EVB</scope></search><sort><creationdate>19911226</creationdate><title>PROCESS FOR 2-DEOXYGLUCOSIDES</title><author>PITCHEN, PHILIPPE ; MIOSKOWSKI, CHARLES</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO9119724A23</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1991</creationdate><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>PITCHEN, PHILIPPE</creatorcontrib><creatorcontrib>MIOSKOWSKI, CHARLES</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>PITCHEN, PHILIPPE</au><au>MIOSKOWSKI, CHARLES</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR 2-DEOXYGLUCOSIDES</title><date>1991-12-26</date><risdate>1991</risdate><abstract>The invention provides a process for the preparation of methyl tri-O-acetyl-2-deoxyglucoside by the reaction of tri-O-acetyl-D-glucal with methanol in the presence of hydrogen bromide or a source thereof. alpha -Methyl tri-O-acetyl-2-deoxyglucoside is especially useful as an intermediate in the preparation of pharmaceutically useful mevalonic acid derivatives.
Cette invention se rapporte à un procédé de préparation de tri-O-acétyle-2-désoxyglucoside de méthyle qui consiste à faire réagir du tri-O-acétyle-D-glucal avec du méthanol en présence de bromure d'hydrogène ou d'une source de bromure d'hydrogène. Le tri-O-acétyle-2-désoxyglucoside de méthyle-alpha est particulièrement utile comme élément intermédiaire dans la préparation de dérivés d'acide mévalonique.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS |
| title | PROCESS FOR 2-DEOXYGLUCOSIDES |
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