MAGNETIC POLYMER PARTICLES
Magnetic polymer particles as carriers of biologically, preferably pharmaceutically active substance are produced. One process of producing the magnetic polymer particles is by treatment of a preferably porous polymer and/or polymerizable monomer with a colloidal solution of magnetic material, the m...
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creator | MOSBACH K H |
description | Magnetic polymer particles as carriers of biologically, preferably pharmaceutically active substance are produced. One process of producing the magnetic polymer particles is by treatment of a preferably porous polymer and/or polymerizable monomer with a colloidal solution of magnetic material, the magnetic material being deposited in the pores or lattice of the polymer. The active substance is associated with the polymer either before or after the magnetization. The substance can also be added to a mixture of monomer and magnetic material for deposition in the pores or lattice of the polymer together with the magnetic material at the polymerization. The produced particles can be used for local concentration of a medicine in an organism or for slow release from a deposit, the particles being retained by a magnetic field within a restricted area, and for example, in so-called affinity chromatography and immuno assays, such as RIA, ELISA.
On produit des particules magnetiques de polymere a titre de support d'une substance presentant une activite biologique, et de preference des proprietes pharmaceutiques. Une methode de production de telles particules consiste a traiter un polymere de preference poreux et/ou un monomere polymerisable a l'aide d'une solution colloidale d'une substance magnetique, ladite substance etant deposee dans les pores ou dans le reseau du polymere. La substance active est associee au polymere avant ou apres magnetisation. La substance peut egalement etre ajoutee a un melange de monomere et de substance magnetique pour se deposer dans les pores ou dans le reseau du polymere en meme temps que la substance magnetique lors de la polymerisation. Les particules ainsi produites peuvent etre utilisees pour concentrer localement un medicament dans un organisme ou pour produire un faible debit de la substance a partir d'une reserve, les particules etant retenues par un champ magnetique dans une zone delimitee et, par exemple dans le cadre de la chromatographie par affinite et d'essais immunologiques tels que RIA, ELISA. |
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On produit des particules magnetiques de polymere a titre de support d'une substance presentant une activite biologique, et de preference des proprietes pharmaceutiques. Une methode de production de telles particules consiste a traiter un polymere de preference poreux et/ou un monomere polymerisable a l'aide d'une solution colloidale d'une substance magnetique, ladite substance etant deposee dans les pores ou dans le reseau du polymere. La substance active est associee au polymere avant ou apres magnetisation. La substance peut egalement etre ajoutee a un melange de monomere et de substance magnetique pour se deposer dans les pores ou dans le reseau du polymere en meme temps que la substance magnetique lors de la polymerisation. Les particules ainsi produites peuvent etre utilisees pour concentrer localement un medicament dans un organisme ou pour produire un faible debit de la substance a partir d'une reserve, les particules etant retenues par un champ magnetique dans une zone delimitee et, par exemple dans le cadre de la chromatographie par affinite et d'essais immunologiques tels que RIA, ELISA.</description><language>eng</language><subject>HUMAN NECESSITIES ; HYGIENE ; INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES ; MEASURING ; MEDICAL OR VETERINARY SCIENCE ; PHYSICS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; TESTING</subject><creationdate>1978</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19781207&DB=EPODOC&CC=WO&NR=7800005A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=19781207&DB=EPODOC&CC=WO&NR=7800005A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>MOSBACH K H</creatorcontrib><title>MAGNETIC POLYMER PARTICLES</title><description>Magnetic polymer particles as carriers of biologically, preferably pharmaceutically active substance are produced. One process of producing the magnetic polymer particles is by treatment of a preferably porous polymer and/or polymerizable monomer with a colloidal solution of magnetic material, the magnetic material being deposited in the pores or lattice of the polymer. The active substance is associated with the polymer either before or after the magnetization. The substance can also be added to a mixture of monomer and magnetic material for deposition in the pores or lattice of the polymer together with the magnetic material at the polymerization. The produced particles can be used for local concentration of a medicine in an organism or for slow release from a deposit, the particles being retained by a magnetic field within a restricted area, and for example, in so-called affinity chromatography and immuno assays, such as RIA, ELISA.
On produit des particules magnetiques de polymere a titre de support d'une substance presentant une activite biologique, et de preference des proprietes pharmaceutiques. Une methode de production de telles particules consiste a traiter un polymere de preference poreux et/ou un monomere polymerisable a l'aide d'une solution colloidale d'une substance magnetique, ladite substance etant deposee dans les pores ou dans le reseau du polymere. La substance active est associee au polymere avant ou apres magnetisation. La substance peut egalement etre ajoutee a un melange de monomere et de substance magnetique pour se deposer dans les pores ou dans le reseau du polymere en meme temps que la substance magnetique lors de la polymerisation. Les particules ainsi produites peuvent etre utilisees pour concentrer localement un medicament dans un organisme ou pour produire un faible debit de la substance a partir d'une reserve, les particules etant retenues par un champ magnetique dans une zone delimitee et, par exemple dans le cadre de la chromatographie par affinite et d'essais immunologiques tels que RIA, ELISA.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</subject><subject>MEASURING</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PHYSICS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>TESTING</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1978</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZJDydXT3cw3xdFYI8PeJ9HUNUghwDAJyfVyDeRhY0xJzilN5oTQ3g4Kba4izh25qQX58anFBYnJqXmpJfLi_uYUBEJg6GhoToQQAAfMgCg</recordid><startdate>19781207</startdate><enddate>19781207</enddate><creator>MOSBACH K H</creator><scope>EVB</scope></search><sort><creationdate>19781207</creationdate><title>MAGNETIC POLYMER PARTICLES</title><author>MOSBACH K H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO7800005A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1978</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES</topic><topic>MEASURING</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PHYSICS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>TESTING</topic><toplevel>online_resources</toplevel><creatorcontrib>MOSBACH K H</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MOSBACH K H</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>MAGNETIC POLYMER PARTICLES</title><date>1978-12-07</date><risdate>1978</risdate><abstract>Magnetic polymer particles as carriers of biologically, preferably pharmaceutically active substance are produced. One process of producing the magnetic polymer particles is by treatment of a preferably porous polymer and/or polymerizable monomer with a colloidal solution of magnetic material, the magnetic material being deposited in the pores or lattice of the polymer. The active substance is associated with the polymer either before or after the magnetization. The substance can also be added to a mixture of monomer and magnetic material for deposition in the pores or lattice of the polymer together with the magnetic material at the polymerization. The produced particles can be used for local concentration of a medicine in an organism or for slow release from a deposit, the particles being retained by a magnetic field within a restricted area, and for example, in so-called affinity chromatography and immuno assays, such as RIA, ELISA.
On produit des particules magnetiques de polymere a titre de support d'une substance presentant une activite biologique, et de preference des proprietes pharmaceutiques. Une methode de production de telles particules consiste a traiter un polymere de preference poreux et/ou un monomere polymerisable a l'aide d'une solution colloidale d'une substance magnetique, ladite substance etant deposee dans les pores ou dans le reseau du polymere. La substance active est associee au polymere avant ou apres magnetisation. La substance peut egalement etre ajoutee a un melange de monomere et de substance magnetique pour se deposer dans les pores ou dans le reseau du polymere en meme temps que la substance magnetique lors de la polymerisation. Les particules ainsi produites peuvent etre utilisees pour concentrer localement un medicament dans un organisme ou pour produire un faible debit de la substance a partir d'une reserve, les particules etant retenues par un champ magnetique dans une zone delimitee et, par exemple dans le cadre de la chromatographie par affinite et d'essais immunologiques tels que RIA, ELISA.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING |
title | MAGNETIC POLYMER PARTICLES |
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