NOVEL SCN10A RNAI AGENTS AND USES THEREOF

The present invention relates to therapeutic compounds, novel RNA interference (RNAi) agents, that decrease expression of the Voltage-Gated Sodium Channel Alpha Subunit 10 (SCN10A) gene, which encodes a subunit of the Nav 1.8 or Nav 1.8 sodium channel. Such RNAi agents decrease levels of intact Nav...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: EGGEN, MariJean, JESSOP, Theodore Curtis, PERKINS, Douglas Raymond, CULLEN, Jennifer Rowe, HUANG, Cheng-Chiu, SHMUSHKOVICH, Taisia, WANG, Jibo
Format: Patent
Sprache:eng ; fre
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