ABA TRI-BLOCK COPOLYMER AND BIORESORBABLE IMPLANTS MADE THEREWITH

A block copolymer comprises an A block and a B block. The A block provides mechanical strength while the B block provides elasticity to the polymeric material. The block copolymer may be an ABA tri-block copolymer. The A block may include one or more of polyglycolide (PGA), polylactic acid (PLA), or...

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Hauptverfasser: KOSSUTH, Mary Beth, DING, Ni, ZONG, Xinhua, ELI, Erik David
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creator KOSSUTH, Mary Beth
DING, Ni
ZONG, Xinhua
ELI, Erik David
description A block copolymer comprises an A block and a B block. The A block provides mechanical strength while the B block provides elasticity to the polymeric material. The block copolymer may be an ABA tri-block copolymer. The A block may include one or more of polyglycolide (PGA), polylactic acid (PLA), or copolymer thereof. The B block may include a random copolymer of (i) glycolide (GA) and/or lactide (LA), (ii) trimethylene carbonate (TMC), and (iii) ε-caprolactone (CL). The block copolymer may cover an implantable device which may be used in delivering immediate hemostasis at a puncture site in a wall of a blood vessel. L'invention concerne un copolymère séquencé comprenant un bloc A et un bloc B. Le bloc A fournit une résistance mécanique tandis que le bloc B fournit une élasticité au matériau polymère. Le copolymère séquencé peut être un copolymère ABA à trois blocs. Le bloc A peut comprendre un ou plusieurs éléments parmi le polyglycolide (PGA), le poly(acide lactique) (PLA) ou un copolymère correspondant. Le bloc B peut comprendre un copolymère aléatoire de (i) glycolide (GA) et/ou lactide (LA), (ii) carbonate de triméthylène (TMC) et (iii) ε-caprolactone (CL). Le copolymère séquencé peut recouvrir un dispositif implantable qui peut être utilisé pour administrer une hémostase immédiate au niveau d'un site de ponction dans une paroi d'un vaisseau sanguin.
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subjects BANDAGES, DRESSINGS OR ABSORBENT PADS
CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES
CHEMISTRY
COMPOSITIONS BASED THEREON
DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF,TUBULAR STRUCTURES OF THE BODY, E.G. STENTS
DISINFECTION, STERILISATION, OR DEODORISATION OF AIR
FILTERS IMPLANTABLE INTO BLOOD VESSELS
FIRST-AID KITS
FOMENTATION
HUMAN NECESSITIES
HYGIENE
MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
ORGANIC MACROMOLECULAR COMPOUNDS
ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES
PROSTHESES
THEIR PREPARATION OR CHEMICAL WORKING-UP
TREATMENT OR PROTECTION OF EYES OR EARS
title ABA TRI-BLOCK COPOLYMER AND BIORESORBABLE IMPLANTS MADE THEREWITH
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