COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF COAGULATION FACTOR XI (FXI)
Compositions and methods useful to inhibiting the expression of Plasma Coagulation Factor XI (FXI) gene and for treatment of FXI -associated diseases and conditions are provided. Provided are FXI dsRNA agents, FXI antisense polynucleotide agents, compositions comprising FXI dsRNA agents, and composi...
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| creator | XIA, Shiwei SHAO, Pengcheng Patrick SHU, Dongxu |
| description | Compositions and methods useful to inhibiting the expression of Plasma Coagulation Factor XI (FXI) gene and for treatment of FXI -associated diseases and conditions are provided. Provided are FXI dsRNA agents, FXI antisense polynucleotide agents, compositions comprising FXI dsRNA agents, and compositions comprising FXI antisense polynucleotide agents that can be used to inhibiting FXI expression in cells and subjects.
L'invention concerne des compositions et des procédés utiles pour inhiber l'expression du gène du facteur XI de coagulation plasmatique (FXI) et pour le traitement maladies et d'affections associées au FXI. La présente invention concerne des agents ARNdb FXI, des agents polynucléotides antisens FXI, des compositions comprenant des agents ARNdb FXI et des compositions comprenant des agents polynucléotides antisens FXI qui peuvent être utilisés pour inhiber l'expression de FXI dans les cellules et les sujets. |
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L'invention concerne des compositions et des procédés utiles pour inhiber l'expression du gène du facteur XI de coagulation plasmatique (FXI) et pour le traitement maladies et d'affections associées au FXI. La présente invention concerne des agents ARNdb FXI, des agents polynucléotides antisens FXI, des compositions comprenant des agents ARNdb FXI et des compositions comprenant des agents polynucléotides antisens FXI qui peuvent être utilisés pour inhiber l'expression de FXI dans les cellules et les sujets.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241128&DB=EPODOC&CC=WO&NR=2024240058A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,777,882,25545,76296</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241128&DB=EPODOC&CC=WO&NR=2024240058A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>XIA, Shiwei</creatorcontrib><creatorcontrib>SHAO, Pengcheng Patrick</creatorcontrib><creatorcontrib>SHU, Dongxu</creatorcontrib><title>COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF COAGULATION FACTOR XI (FXI)</title><description>Compositions and methods useful to inhibiting the expression of Plasma Coagulation Factor XI (FXI) gene and for treatment of FXI -associated diseases and conditions are provided. Provided are FXI dsRNA agents, FXI antisense polynucleotide agents, compositions comprising FXI dsRNA agents, and compositions comprising FXI antisense polynucleotide agents that can be used to inhibiting FXI expression in cells and subjects.
L'invention concerne des compositions et des procédés utiles pour inhiber l'expression du gène du facteur XI de coagulation plasmatique (FXI) et pour le traitement maladies et d'affections associées au FXI. La présente invention concerne des agents ARNdb FXI, des agents polynucléotides antisens FXI, des compositions comprenant des agents ARNdb FXI et des compositions comprenant des agents polynucléotides antisens FXI qui peuvent être utilisés pour inhiber l'expression de FXI dans les cellules et les sujets.</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMPOSITIONS THEREOF</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZAh09vcN8A_2DPH09wtWcPRzUfB1DfHwdwlWcPMPUvD08_B0Asr5uSu4RgQEuQYHA5Up-LspOPs7uof6OIJ0Kbg5OocA1UZ4Kmi4RXhq8jCwpiXmFKfyQmluBmU31xBnD93Ugvz41OKCxOTUvNSS-HB_IwMjEyMTAwNTC0dDY-JUAQBqTDAr</recordid><startdate>20241128</startdate><enddate>20241128</enddate><creator>XIA, Shiwei</creator><creator>SHAO, Pengcheng Patrick</creator><creator>SHU, Dongxu</creator><scope>EVB</scope></search><sort><creationdate>20241128</creationdate><title>COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF COAGULATION FACTOR XI (FXI)</title><author>XIA, Shiwei ; SHAO, Pengcheng Patrick ; SHU, Dongxu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024240058A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMPOSITIONS THEREOF</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>XIA, Shiwei</creatorcontrib><creatorcontrib>SHAO, Pengcheng Patrick</creatorcontrib><creatorcontrib>SHU, Dongxu</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>XIA, Shiwei</au><au>SHAO, Pengcheng Patrick</au><au>SHU, Dongxu</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF COAGULATION FACTOR XI (FXI)</title><date>2024-11-28</date><risdate>2024</risdate><abstract>Compositions and methods useful to inhibiting the expression of Plasma Coagulation Factor XI (FXI) gene and for treatment of FXI -associated diseases and conditions are provided. Provided are FXI dsRNA agents, FXI antisense polynucleotide agents, compositions comprising FXI dsRNA agents, and compositions comprising FXI antisense polynucleotide agents that can be used to inhibiting FXI expression in cells and subjects.
L'invention concerne des compositions et des procédés utiles pour inhiber l'expression du gène du facteur XI de coagulation plasmatique (FXI) et pour le traitement maladies et d'affections associées au FXI. La présente invention concerne des agents ARNdb FXI, des agents polynucléotides antisens FXI, des compositions comprenant des agents ARNdb FXI et des compositions comprenant des agents polynucléotides antisens FXI qui peuvent être utilisés pour inhiber l'expression de FXI dans les cellules et les sujets.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | COMPOSITIONS AND METHODS FOR INHIBITING EXPRESSION OF COAGULATION FACTOR XI (FXI) |
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