KETAMINE LIQUID PREPARATION AND USE THEREOF

The present application discloses a ketamine liquid preparation. The ketamine liquid preparation comprises ketamine or a pharmaceutically acceptable salt thereof, at least two lower alcohols and water, and the pH value of the liquid preparation is 2.5-7.5. The liquid preparation of the present application is administered via oral mucosa, and has simple formula, high stability, fast absorption, high bioavailability, simple administration mode and good compliance. The preparation of the present application can be used for the prevention, alleviation or treatment of major depression, unipolar depression, treatment-resistant depression, intractable depression, agitated depression, and bipolar depression. La présente invention concerne une préparation liquide de kétamine. La préparation liquide de kétamine comprend de la kétamine ou un sel pharmaceutiquement acceptable de celle-ci, au moins deux alcools inférieurs et de l'eau, et la valeur de pH de la préparation liquide est de 2,5-7,5. La préparation liquide de l