METHODS OF MINIMISING EFFECTS OF SMOKE EXPOSURE
The present invention relates to compositions, methods and kits for the treatment or prevention of effects of smoke exposure. In particular, the compositions, methods and kits are particularly useful, but not limited to, the treatment or prevention of acute or chronic smoke exposure. In one aspect,...
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| creator | PICKERING, Raelene Jane THOMAS, Merlin Christopher |
| description | The present invention relates to compositions, methods and kits for the treatment or prevention of effects of smoke exposure. In particular, the compositions, methods and kits are particularly useful, but not limited to, the treatment or prevention of acute or chronic smoke exposure. In one aspect, the present invention provides a method of treating or preventing obstructive pulmonary disease, associated with or caused by exposure to smoke, in a subject in need thereof, the method comprising administering to the subject an antisense oligonucleotide (AON) that promotes the production of endogenous soluble RAGE, treating or preventing obstructive pulmonary disease, associated with or caused by exposure to smoke in the subject.
La présente invention concerne des compositions, des procédés et des kits pour le traitement ou la prévention d'effets de l'exposition à la fumée. En particulier, les compositions, les procédés et les kits sont particulièrement utiles, mais sans y être limités, pour le traitement ou la prévention d'une exposition à la fumée aiguë ou chronique. Selon un aspect, la présente invention concerne une méthode de traitement ou de prévention d'une maladie pulmonaire obstructive, associée ou provoquée par une exposition à la fumée, chez un sujet en ayant besoin, la méthode comprenant l'administration au sujet d'un oligonucléotide antisens (AON) qui favorise la production de RAGE soluble endogène, le traitement ou la prévention d'une maladie pulmonaire obstructive, associée ou provoquée par l'exposition à la fumée chez le sujet. |
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La présente invention concerne des compositions, des procédés et des kits pour le traitement ou la prévention d'effets de l'exposition à la fumée. En particulier, les compositions, les procédés et les kits sont particulièrement utiles, mais sans y être limités, pour le traitement ou la prévention d'une exposition à la fumée aiguë ou chronique. Selon un aspect, la présente invention concerne une méthode de traitement ou de prévention d'une maladie pulmonaire obstructive, associée ou provoquée par une exposition à la fumée, chez un sujet en ayant besoin, la méthode comprenant l'administration au sujet d'un oligonucléotide antisens (AON) qui favorise la production de RAGE soluble endogène, le traitement ou la prévention d'une maladie pulmonaire obstructive, associée ou provoquée par l'exposition à la fumée chez le sujet.</description><language>eng ; fre</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS THEREOF ; CULTURE MEDIA ; ENZYMOLOGY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241128&DB=EPODOC&CC=WO&NR=2024239050A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241128&DB=EPODOC&CC=WO&NR=2024239050A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>PICKERING, Raelene Jane</creatorcontrib><creatorcontrib>THOMAS, Merlin Christopher</creatorcontrib><title>METHODS OF MINIMISING EFFECTS OF SMOKE EXPOSURE</title><description>The present invention relates to compositions, methods and kits for the treatment or prevention of effects of smoke exposure. In particular, the compositions, methods and kits are particularly useful, but not limited to, the treatment or prevention of acute or chronic smoke exposure. In one aspect, the present invention provides a method of treating or preventing obstructive pulmonary disease, associated with or caused by exposure to smoke, in a subject in need thereof, the method comprising administering to the subject an antisense oligonucleotide (AON) that promotes the production of endogenous soluble RAGE, treating or preventing obstructive pulmonary disease, associated with or caused by exposure to smoke in the subject.
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE |
| title | METHODS OF MINIMISING EFFECTS OF SMOKE EXPOSURE |
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