DESIGN AND METHOD OF GENERATING SCARLESS CIRCULAR RNA

A method of making circularization of an RNA of interest without a use of permuted intron-exon (PIE) includes: providing a DNA (deoxyribonucleic acid) construct, wherein the DNA construct includes a Group I intron-based ribozyme, a sequence of interest, and a target sequence; causing an RNA to be tr...

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Hauptverfasser: CHATTERJI, Monalisa, MEERA MOHAIDEEN, Asma, RANGANATHAN, Anirudh, KHEDKAR, Anand, DWARAKANATH, Srivatsa
Format: Patent
Sprache:eng ; fre
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