INJECTABLE PHARMACEUTICAL FORMULATIONS

Provided herein are injectable pharmaceutical formulations, methods for their production, kits, and uses thereof in the treatment of diseases or disorders. The injectable pharmaceutical formulations include a psychopharmaceutical agent, a release modifier, and an aqueous vehicle. The pharmaceutical...

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Hauptverfasser: SHUKOOR, Mohammed I, MORGAN, Michael E, VARTY, Geoffrey B, PALFREYMAN, Michael, NIVOROZHKIN, Alex, AVERY, Kenneth L, FENG, Ju, PATHARE, Pradip M
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creator SHUKOOR, Mohammed I
MORGAN, Michael E
VARTY, Geoffrey B
PALFREYMAN, Michael
NIVOROZHKIN, Alex
AVERY, Kenneth L
FENG, Ju
PATHARE, Pradip M
description Provided herein are injectable pharmaceutical formulations, methods for their production, kits, and uses thereof in the treatment of diseases or disorders. The injectable pharmaceutical formulations include a psychopharmaceutical agent, a release modifier, and an aqueous vehicle. The pharmaceutical formulations allow for a time-restricted temporal controlled-release of the psychopharmaceutical agent upon administration by injection such as subcutaneous injection. The diseases or disorders treatable with the pharmaceutical formulations include, for example, neuropsychiatric diseases or disorders or inflammatory diseases or disorders, such as a central nervous system (CNS) disorder and/or psychological disorder, including those associated with a 5-HT2 receptor. L'invention concerne des formulations pharmaceutiques injectables, des procédés pour leur production, des kits et leurs utilisations dans le traitement de maladies ou de troubles. Les formulations pharmaceutiques injectables comprennent un agent psychopharmaceutique, un modificateur de libération et un véhicule aqueux. Les formulations pharmaceutiques permettent une libération contrôlée temporelle limitée dans le temps de l'agent psychopharmaceutique lors de l'administration par injection telle qu'une injection sous-cutanée. Les maladies ou troubles pouvant être traités avec les formulations pharmaceutiques comprennent, par exemple, des maladies ou troubles neuropsychiatriques ou des maladies ou troubles inflammatoires, tels qu'un trouble du système nerveux central (SNC) et/ou un trouble psychologique, y compris ceux associés à un récepteur 5-HT2.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title INJECTABLE PHARMACEUTICAL FORMULATIONS
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