COMPOSITIONS AND METHODS FOR REGULATING MAPT

The disclosure relates to small interfering RNA (siRNA) molecules targeting MAPT and adeno-associated viral (AAV) particles encoding the same for treating tauopathies. L'invention concerne de petites molécules d'ARN interférent (ARNsi) ciblant MAPT et des particules virales adéno-associées...

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Hauptverfasser: LI, Jiangyu, HOU, Jinzhao, COLPAN, Cansu, KNOLL, Elisabeth, CARTER, Todd, BAO, Hechen, NONNENMACHER, Mathieu Emmanuel, LAKS, Dan Richard, SAH, Dinah Wen-Yee, LEE, Shiron Jessie, SIVASANKARAN, Rajeev Nambiar, MOYER, Tyler Christopher, JIN, Wen, DECKERT, Jochen, HULTSCH, Kathrin, LIU, Wencheng
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creator LI, Jiangyu
HOU, Jinzhao
COLPAN, Cansu
KNOLL, Elisabeth
CARTER, Todd
BAO, Hechen
NONNENMACHER, Mathieu Emmanuel
LAKS, Dan Richard
SAH, Dinah Wen-Yee
LEE, Shiron Jessie
SIVASANKARAN, Rajeev Nambiar
MOYER, Tyler Christopher
JIN, Wen
DECKERT, Jochen
HULTSCH, Kathrin
LIU, Wencheng
description The disclosure relates to small interfering RNA (siRNA) molecules targeting MAPT and adeno-associated viral (AAV) particles encoding the same for treating tauopathies. L'invention concerne de petites molécules d'ARN interférent (ARNsi) ciblant MAPT et des particules virales adéno-associées (AAV) codant pour celles-ci pour traiter des tauopathies.
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
title COMPOSITIONS AND METHODS FOR REGULATING MAPT
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