PROCESS FOR THE PREPARATION OF SUVOREXANT
The present invention relates to a process for the preparation of Suvorexant (1) having a purity greater than 99.5% by High-performance liquid chromatography (HPLC). The present invention also relates to novel process for the preparation of 5 (R)-1-benzyl-5-methyl-1,4-diazepane tartrate (7). The pre...
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| creator | KOTHAKONDA, Kiran Kumar PULLAGURLA, Manik Reddy NAMANA, Sureshbabu PITTA, Bhaskar Reddy RANGISETTY, Jagadeesh Babu |
| description | The present invention relates to a process for the preparation of Suvorexant (1) having a purity greater than 99.5% by High-performance liquid chromatography (HPLC). The present invention also relates to novel process for the preparation of 5 (R)-1-benzyl-5-methyl-1,4-diazepane tartrate (7). The present invention further relates to a process for pure solid forms of Suvorexant (1).
La présente invention concerne un procédé de préparation de suvorexant (1) ayant une pureté supérieure à 99,5% par chromatographie liquide haute performance (HPLC). La présente invention concerne également un nouveau procédé de préparation du tartrate de 5 (R)-1-benzyl-5-méthyl -1,4-diazépane (7). La présente invention concerne en outre un procédé pour des formes solides pures de suvorexant (1). |
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La présente invention concerne un procédé de préparation de suvorexant (1) ayant une pureté supérieure à 99,5% par chromatographie liquide haute performance (HPLC). La présente invention concerne également un nouveau procédé de préparation du tartrate de 5 (R)-1-benzyl-5-méthyl -1,4-diazépane (7). La présente invention concerne en outre un procédé pour des formes solides pures de suvorexant (1).</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241003&DB=EPODOC&CC=WO&NR=2024201424A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20241003&DB=EPODOC&CC=WO&NR=2024201424A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KOTHAKONDA, Kiran Kumar</creatorcontrib><creatorcontrib>PULLAGURLA, Manik Reddy</creatorcontrib><creatorcontrib>NAMANA, Sureshbabu</creatorcontrib><creatorcontrib>PITTA, Bhaskar Reddy</creatorcontrib><creatorcontrib>RANGISETTY, Jagadeesh Babu</creatorcontrib><title>PROCESS FOR THE PREPARATION OF SUVOREXANT</title><description>The present invention relates to a process for the preparation of Suvorexant (1) having a purity greater than 99.5% by High-performance liquid chromatography (HPLC). The present invention also relates to novel process for the preparation of 5 (R)-1-benzyl-5-methyl-1,4-diazepane tartrate (7). The present invention further relates to a process for pure solid forms of Suvorexant (1).
La présente invention concerne un procédé de préparation de suvorexant (1) ayant une pureté supérieure à 99,5% par chromatographie liquide haute performance (HPLC). La présente invention concerne également un nouveau procédé de préparation du tartrate de 5 (R)-1-benzyl-5-méthyl -1,4-diazépane (7). La présente invention concerne en outre un procédé pour des formes solides pures de suvorexant (1).</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNAMCPJ3dg0OVnDzD1II8XBVCAhyDXAMcgzx9PdT8HdTCA4N8w9yjXD0C-FhYE1LzClO5YXS3AzKbq4hzh66qQX58anFBYnJqXmpJfHh_kYGRiZGBoYmRiaOhsbEqQIA0NYlag</recordid><startdate>20241003</startdate><enddate>20241003</enddate><creator>KOTHAKONDA, Kiran Kumar</creator><creator>PULLAGURLA, Manik Reddy</creator><creator>NAMANA, Sureshbabu</creator><creator>PITTA, Bhaskar Reddy</creator><creator>RANGISETTY, Jagadeesh Babu</creator><scope>EVB</scope></search><sort><creationdate>20241003</creationdate><title>PROCESS FOR THE PREPARATION OF SUVOREXANT</title><author>KOTHAKONDA, Kiran Kumar ; PULLAGURLA, Manik Reddy ; NAMANA, Sureshbabu ; PITTA, Bhaskar Reddy ; RANGISETTY, Jagadeesh Babu</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_WO2024201424A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>KOTHAKONDA, Kiran Kumar</creatorcontrib><creatorcontrib>PULLAGURLA, Manik Reddy</creatorcontrib><creatorcontrib>NAMANA, Sureshbabu</creatorcontrib><creatorcontrib>PITTA, Bhaskar Reddy</creatorcontrib><creatorcontrib>RANGISETTY, Jagadeesh Babu</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>KOTHAKONDA, Kiran Kumar</au><au>PULLAGURLA, Manik Reddy</au><au>NAMANA, Sureshbabu</au><au>PITTA, Bhaskar Reddy</au><au>RANGISETTY, Jagadeesh Babu</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>PROCESS FOR THE PREPARATION OF SUVOREXANT</title><date>2024-10-03</date><risdate>2024</risdate><abstract>The present invention relates to a process for the preparation of Suvorexant (1) having a purity greater than 99.5% by High-performance liquid chromatography (HPLC). The present invention also relates to novel process for the preparation of 5 (R)-1-benzyl-5-methyl-1,4-diazepane tartrate (7). The present invention further relates to a process for pure solid forms of Suvorexant (1).
La présente invention concerne un procédé de préparation de suvorexant (1) ayant une pureté supérieure à 99,5% par chromatographie liquide haute performance (HPLC). La présente invention concerne également un nouveau procédé de préparation du tartrate de 5 (R)-1-benzyl-5-méthyl -1,4-diazépane (7). La présente invention concerne en outre un procédé pour des formes solides pures de suvorexant (1).</abstract><oa>free_for_read</oa></addata></record> |
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| title | PROCESS FOR THE PREPARATION OF SUVOREXANT |
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